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  #10 (permalink)  
Old 04-20-2006, 05:51 PM
rzrbks's Avatar
rzrbks rzrbks is offline
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I am a: Type 1.5
 
Join Date: Sep 2003
Location: Hogwarts, Hobbiton, the Galactic Milieu &Ks when I have to be here
Posts: 4,321
Here's the best detailed description I've been able to find, so far........


so, if I read this right there could be a peak at 8-9 hours, if there's going to be one.


and the 2nd part says you're covered for 15-18 hours.

Quote:
The relative bioavailability of NovoLog Mix 70/30 compared to NovoLog and Novolin 70/30 indicates that they are absorbed to similar degrees. In euglycemic clamp studies in healthy volunteers (n=23) after dosing with 0.2 U/kg of NovoLog Mix 70/30, a mean maximum serum concentration (cmax) of 23.4 ± 5.3 mU/L was reached after 60 minutes. The mean half-life (t1/2) of NovoLog Mix 70/30 was about 8 to 9 hours. Serum insulin levels returned to baseline 15 to 18 hours after a subcutaneous dose. Similar data were seen in a separate euglycemic clamp study in healthy volunteers (n=24) after dosing with 0.3 U/kg of NovoLog Mix 70/30. A cmax of 61.3 ± 20.1 mU/L was reached after 85 minutes. Serum insulin levels returned to baseline 12 hours after a subcutaneous dose.
http://www.rxlist.com/cgi/generic4/novologmix_cp.htm
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