| I'm also on Symlin and I've noticed that I have to do an extended bolus (I'm a pumper) when I take it. I've heard recommendations from other posters on MDI to split their bolus up. What may be happening is that the delay in digestion is affecting your bg levels and you are actually under dosing your boluses. If you take more insulin for your bolus and split it, say take 1/2 when you eat and 1/2 approx 2 hours later, you may find the results you are looking for. I watched the effects of Symlin on a CGMS and it absolutely delays the digestion and subsequent spike in blood glucose. | 
