| I had this discussion with my endo when I was having some severe bouts of hi bgs that would go on for a week at times.
He said this was insulin resistance by definition. It required a big time change in the basal rate, and the insulin to carb ratio went off the scale at the same time.
Found the answer to it last year when I started using Symlin. I quickly found the hi's could be beat down by taking a very hi dose of Symlin. Usually it will take at least 15 units, sometimes it take two or three of those in a row, but it will stop the hi insulin resistant periods I continure to have.
After I reported this to the endo he said that confirmed his suspicions, he believes I am experiencing releases of glucogon in large amounts. Said the Symlin will stop either the glucogon, or whatever is signaling its release. I was not clear on that point.
With that I have been trying to find out as much as I can about this glucogon. I read this summer where the thinking is to lower the carb intake and that should lower the glucogon stored. I have been working to lower my carb intake since. Yes, it has reduced the number of these difficult sessions, and I think they are not so bad as before. Last one was about two weeks back, went to 360 right after a dinner, hit it with 15 unit Symlin mixed with 4 units Novolog and it leveled out within an hour with a reoccurrance next morning after breakfast that went only to 250. Quelled that one and have been ok since.
Much better than the 400's I was getting before this.
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Type 1 since September 1978. Pumper since 1998.
I want to die sleeping peacefully, - like my grandma; not screaming with horror, - like those, who were as passangers in her car. |