| If your GAD65 antibody tests positive, then you have LADA (Latent Autoimmune Diabetes of Adults), also sometimes called T1.5. The autoimmune reaction is stronger at the beginning stages showing a large number of antibodies. As the attack on the beta cells continues and beta cells begin to die off, the number of antibodies decreases. When all the beta cells are gone, the antibodies disappear as well.
So, if ANY antibodies are detected in a GAD65 antibody test, it is positive for LADA (T1.5). If a GAD65 antibody test shows NO antibodies, it is possible that the beta cells have all died and the attacking antibodies have disappeared. Therefore, a positive result is definitely a positive while a negative result in an insulin dependent person can mean the person is T2... OR it can mean that the person is LADA (T1.5), has no beta cells left and the autoimmune attack has ceased. Clear as mud?
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NoraWI
LADA (T1)
Lantus, Novolog, levothyroxine
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