I don't know that the Opticlick CAN'T be X-rayed, but that is what I told them. People X-ray laptops all the time (I have a pool of 12 at work that have gone through X-ray scans probably 100 times). However I decided not to risk having Lantus Drama if my pen went haywire, and so I told them it had to be hand inspected.
Seriously, it was NOT a problem with security - just a little planning and organization on my part and everything went very smoothly. Don't let it ruin your plans, really.
