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Thread: Apidra

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#15 (permalink)

01-29-2007, 09:21 PM

BriOnH

Senior Member

I am a: Type 1

Join Date: Oct 2005

Location: Sacramento California

Posts: 2,515

Quote:

Originally Posted by jen_slc

Humalog = generic name 'lispro' = a lysine and a proline are reversed from the "normal" insulin structure

Novolog = generic name 'aspart' = a proline is substituted with aspartic acid

Apidra = generic name 'glulisine' = an asparagine is replaced by lysine and a different lysine is replaced by glutamic acid

Do you know if the amino acid switches occur at the active site of the enzyme Jen?

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Brian Hartigan