Quote:
Originally Posted by Oradev  ... I take Lantus in the am and pm. I get great results from Lantus during the day, but the mornings tend to sometimes give me a problem. ... |
It sounds like your morning Lantus doesn't always last the 24 hours. Which is why you sometimes have high morning blood glucose levels. Within-individual absorption variability is about 25% for Lantus. Which is why your morning BG is often OK but sometimes it isn't.
Lantus is marketed as a once-a-day insulin, and Aventis is sticking to their guns on this. The reality for many of us is that it doesn't always last that long. Also bear in mind that, the bigger the dose, the longer it lasts. If you are eating low-carb and on a smaller dose, you really need to split it over two shots.
I would suggest splitting the dose and seeing how that works. You may find that it sorts the problem out. If you are still having high morning BG, you can consider replacing the evening Lantus shot with NPH. It is more effective in dealing with the DP and bridges the gap in Lantus action, at the same time.
The only problem with NPH is that its absorption and action is even more variable (about 30%) than Lantus is. But if you are just using small amounts, you should be a lot better off.
