[SharpTail]

What I will talk about here may be inconsequential to some since the medication I am taking for meal boluses is only available in the clinical trial I am involved in. I have commented in past posts about how fast the action of the inhaled Technosphere Insulin is. I recorded on the weekend the use of the TI insulin for a correction I had to make.

We travelled from home to go to a restaurant and as it turned out I forgot the TI insulin. After an hour drive home my Blood Glucose measurement was 22.1 (390). I have always had no patience to wait to get that kind of number back into the normal range and have learned to treat it very aggressively. However, such a high number it has always been a struggle to get good action from my fast insulin (including Humalog before the trial), probably due to the increased insulin resistance referred to by others on this forum.

I took a bolus of TI insulin what would probably be the equivalent of 10U of Humalog for me. I then got on our treadmill and reached a fast walking pace to keep my heart rate between 120-135. Following are my BG readings during and after a 1 hour aerobic session:

Beginning BG 22.1 (390)
After 1/2 hour 8.9 (160)
After 1 hour 5.3 (100)

2 hour mark 5.2 (100)
(1 hour after exercise)

So in one hour I dropped my BG from 22.1 to a normal 5.3. A couple of interesting things happened. Most of the action of the insulin appears to have taken place in the first 1/2 hour. Also in the one hour after I finished the exercise session my blood sugar was stable, indicating that the action of the insulin was completed. In other words, it appears that I basically used up the entire dose of insulin in one hour rather than the 2-2 1/2 hours that it normally functions for.

I know without a bolus of insulin I can drop my BG level a bit with an aerobic activity. But with the addition of the TI insulin being rapidly used, I assume through increased blood flow to the lungs, the result seems to be very dramatic. The only other fast acting insulin I have used is Humalog and I could not expect to get this kind of result from it.

I would like to ask other members of the forum if they have used any other injected insulins to give this dramatic effect when combined with an aerobic activity?
Pat