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Originally Posted by Real4  Why is that a bad definition? It is a functional definition for calibrating an insulin dose. You need a single measure so that all forms and types of insulin can have the same meaning - in terms of the insulin's physiological effects on the body. |
Because a 'unit of insulin' is a measurement of of the amount of protein (insulin) found in a quantitative dosage. A measurement in a measurement. I don't know how old the study is, but today, relative to BlueSky's findings, we can accurately know how many insulin proteins are in a unit.
The weight of the suspension fluid, minus the weight of the sf with insulin in it (and 'fillers') , divided by the mass of the protien of the weight found = the amount of insulin in 1 unit of insulin. Quality assurance of the test in a rabbit is fine, but it doesn't, imho, define the quantitate definition of a unit of insulin.
