Steph, I see that you are a T1 so you need to be aware that drugs or supplements that stimulate insulin production won't do you much good. I have used Metformin with some success to moderate the effects of the Dawn Phenomenon. This is because Meformin inhibits the production of hepatic glucose. I didn't reduce my insulin dosage at all. I just didn't need to bolus as much before breakfast. I had no problems with the nausea, and I suggest that you try it. Metformin is a cheap and safe drug.
I can't comment on Hyponidd as I haven't used it. It appears to have a moderate affect when used with T2 diabetics, at least part of which is because it stimulates insulin production. There is probably no harm in trying it, but don't expect too much. Here is some info I found :
Quote:
Antidiabetic drug could have three sites of action: reducing insulin resistance, increasing insulin secretion or decreasing the absorption of glucose from the intestine. Most of the ayurvedic drugs claim to influence all the three sites of action. Some of the ingredients of Hyponidd have been reported to influence the production of insulin and reduce the deleterious effects of glucose, like peroxidation[13]. It is also claimed that Gynmnema Sylvestre increased the production of insulin, decreases its destruction and thus normalizes blood sugar.[17]. In our study, we found a slight (but non-significant) increase in both insulin and C-peptide levels suggesting that the drug probably works by stimulating beta cells. However, further studies are needed to prove this effect.....
None of the earlier studies or our own study showed any significant adverse effects for Hyponidd implying that the drug is safe.
In conclusion, the results of this double blind randomized trial shows that Hyponidd, a herbal anti-diabetic drug reduces fasting and postprandial plasma glucose slightly and the HbA1c levels slightly, in a group of type 2 diabetic patients with secondary failure to oral hypoglycemic agents. One could argue that this is a group of patients in whom one would not expect dramatic results as they are already in a stage of secondary failure. The effect of the drug might be more impressive if used in newly diagnosed type 2 diabetic patients. Moreover another limitation of the study is that the sample size is small. More studies are clearly needed to determine the efficacy and mechanism of action of Hyponidd in different groups of type 2 diabetic patients.
Evaluation of Safety and Efficacy of Hyponidd, an Ayurvedic compound: a Double Blind, Placebo Controlled Study in Type 2 Diabetic Patients with Secondary Failure to Oral Drugs :Poongothai S, Karkuzhali K, Sharadha J, Deepa R, Mohan V, , Int J Diab De |
