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...What happens if you're low at some point through out the day-- because it's a slow release insulin, doesn't that mean that..while you're low you could potentially have insulin in you making you go lower?...
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Yes, it does. The best you can do is ensure that this basal insulin action is as steady and consistent as possible, so it doesn't mess your blood sugar levels around. NPH is also a long acting insulin. It peaks at 6 - 10 hours after injecting it, and the action tails off for the next 8 hours. This why NPH really needs to be taken in two shots. But even then, it doesn't work that well. Lantus and Levemir do a much better job
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