| For myself, the answer to this question is equal to the answer of another, which is: at what blood glucose level does organ damage and other complications begin? Unfortunately, there is no clear cut answer to this question and maybe there cannot be one.
From everything I have read on this subject, the conclusion I have "settled" for, is that damage occurs at sustained BG levels of over 140 mg/dl. So this is the number I work at staying below at all times by whatever means that become necessary.
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The person who says it cannot be done should not interrupt the person doing it. | 
