[lottadata]

Dave,

Is your doctor who knows about MODY in Massachusetts? If so, PLEASE let me know who it is. I'm in WMass and have yet to find an Endo who has ever heard anything about it

For bg control, I use tiny doses of insulin and that gives me extremely good control. I love the flexibility available with an insulin pen. If I'm eating a low carb meal, I use no insulin at all. For a higher carb meal I'll use 2-4 units (rarely 4.) Often I do 2 units and then an hour, one more if I'm not back where I want to be. I am usually around 100 at 2 hours. I try to avoid going over 120 at 1 hour at all times. Mostly it works.

Novolog works very well. I could not make humalog work at all--I went high and then low and it got worse, the longer I used it. I recently heard from another MODY person who had the identical experience with Humalog as I did. (One my docs just shook their heads about, but EVERYTHING about MODY makes them shake their heads.)

One thing that also might be worth checking out, is that I've seen a paradoxical effect. TOO much basal insulin will push my post-meal blood sugars UP, not down, though I don't ever catch the hypo. What happens is I get bursts of those counterregulatory hormones that push up blood sugar and make me more insulin resistant.

As strange as it sounds, cutting back a bit on the prandin dose might work better if you are experiencing anything like that. It is certainly worth a try. I found I had to cut back on Lantus to get better numbers.