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  #23 (permalink)  
Old 03-30-2008, 09:02 AM
lottadata lottadata is offline
Member
I am a: Type 1.5
 
Join Date: Apr 2006
Location: Massachusetts
Posts: 130
Lantus is the WRONG insulin for MODY.

The defect is in post-prandial secretion. When I get to where I have enough Lantus in me to begin to cover meals, I'm hypoing at night and having an extremely fast pulse all day thanks to counterregulation.

Very small doses of meal time insulin work much better for me. 2-4 units, tops. That drops what would be a 280 to 120.

For some people diagnosed with MODY Byetta works extremely well, too.

I got just about normal blood sugars with the other incretin drug, Januvia, for a while, but it impacts the immune system and looks like it might be very dangerous for a melanoma survivor (which I am) so I had to stop taking it. Plus by 3 months the side effects were getting intolerable: nonstop splitting headache and my digestive system ground to a complete halt.

Byetta doesn't affect the immune system, but the one time I tried it, it was a bit overwhelming for me. My blood sugars are a bit worse now, so I might give it another try.

If you have LADA, on the other hand, Lantus might be better, but you still need the meal time insulin.

I did 6 weeks of the Bernstein diabetes diet with no insuiln this past winter to lose some of the weight I put on when I stopped metformin and shifted from R to Novolog. I was eating no more than 6 grams per meal and seeing okay blood sugars
but I got hungrier and hungrier the longer I did it until it was impossible to continue. I am not at all hungry when I use post-meal insulin.

I'll email you privately about the doc.
__________________
A1c 5.7% 10 years after diagnosis.
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