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  #5 (permalink)  
Old 04-25-2008, 07:09 AM
Eddy's Avatar
Eddy Eddy is offline
Senior Member
I am a: Type 1
 
Join Date: Jan 2008
Location: Kansas, US
Posts: 922
Quote:
Originally Posted by BlueSky View Post
I put my money on the increased insulin resistance. Eating more carbohydrate than your body needs at the time and pumping in insulin to cover it will obviously increase insulin resistance. How else can organ and muscle cells deny entry to unwanted glucose? The problem is that the effect continues long after the meal has been digested, the stomach has emptied and the bolus insulin has run its course. If you are not eating like this at every meal and eevery day, increasing you basal won't help.
Makes sense. Levemir is short-lived enough that I could increase my overnight dose. (Of course, eating sane meals probably is a better tactic.)

It would be intriguing to see if people prone to weight gain have smaller postprandial spikes than those who seem to have no trouble keeping the weight off.

Quote:
Originally Posted by Real4 View Post
How does one eat 250 grams of CHO in a single meal? 250 grams of CHO is equivalent to about 12 ounces (2 oz = 42 grams) of dry spaghetti. Cooked that would easily overflow any plate I've ever seen!!!
Hungry before, stuffed afterwards. A quart of potato-based soup, a fair amount of pasta, a few slices of bread, another dish... it's doable. Yes, it requires well more than one plate -- not to mention an hour (sometimes a little more) to eat everything.

You should have seen my pre-DX meals. And I was still losing weight...

Quote:
Originally Posted by Real4 View Post
P.S. On the basal/bolus question, I think a better explanation than usually given is that the liver stores about half of the carbohydrates it normally takes in and then gradually releases that as glucose during non-digestives hours. The 50/50 ratio is an outcome of that more than anything else.
Hmmmm. So we high-basal people just like to stockpile, eh?

Quote:
Originally Posted by xMenace View Post
Resaurants? You have to consider at least some protein and probably at least as many calories in fats. This could easily be our Chinese/Pizza syndrome. Such meals are nearly impossible to nail perfectly.
I've heard the protein/fat theory. Never happens to me with sane-sized meals. Perhaps excess * gets converted to glucose; that's what I was trying to say by "releasing more glucose". And if high-basal people like to "stockpile", perhaps that's why I need a crazy-large meal to observe the latent upward drift...

FWIW, I actually seem to have an easier time nailing those huge meals. Large quantities of food digest more predictably, and any insulin-measurement errors are dwarfed by the total dose size. The problem is guesstimating the portion size... but spreading the release (of both glucose and insulin) over five hours instead of two makes things easier to me.
__________________
Eddy


DXed 2007/04 = advanced-stage DKA, A1c of 12.9%, and BMI of 21.3
post-DX A1c = 5.4% @ 2008/07; 5.2% @ 2008/04; 5.3% @ 2007/12; 5.3% @ 2007/08
c-peptide = 0.0% @ 2008/07
current BMI = 26.0 (86kg on 182cm); want to get back to 23-24
basal = 2U human N @ 0630, 5U detemir @ 0630, 8U detemir @ 1130, 19U detemir @ 2030
bolus = 1:15 I:C ratio; varying mix of aspart, human R, human N

not a low-CHO eater... not even close!
last updated 2008/07/19

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