Not much of a fan of these kind of press releases - The study isn't being published until July, and they don't reveal anywhere near enough information to make any kind of judgement. There is no mention of the magnitude of the effect only that it lowered blood sugar.
<puts cynical hat on> if the effect was large then I get the feeling they would mentioned it.
This is marketing hype really rather than news.
You may want to know what the fuss is all about though. I checked through Pubmed, and from a very brief search, I didn't find any previous research looking at diabetes in humans, aspirin and BG, but I did find one on rodents
In rodents aspirin suppresses the production of IkappaB kinase beta by the liver. This enzyme increases hepatic insulin resistance in response to inflammation. Aspirin reduces inflammation, and also reduces the production of this kinase and so reverses insulin resistance in the liver.
Reversal of obesity- and diet-induced insulin resi...[Science. 2001] - PubMed Result
which explains why they bang on so much about insulin resistance in the article. And get it hopelessly wrong.
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New research conducted by Spanish researchers finds that healthy obese people who take aspirin actually increase their levels of insulin
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they found higher levels of insulin in their test subjects - this means that the main effect of aspirin can't be on suppressing IkappaB kinase beta.
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actually increase their levels of insulin, reducing the chance of developing insulin resistance. During insulin resistance, the body produces too little of the hormone and fails to effectively regulate the metabolism of fats, proteins and sugars.
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This second statement is NONSENSE.
first off insulin resistance is not determined by the amount of circulating insulin. In muscle, insulin resistance is determined by the amount of glucose transporters in the cell wall - produce fewer glucose transporters, less glucose gets into the cell each time insulin stimulates the cell, therefore you need more insulin to produce the same lowering of blood glucose. Insulin resistance causes insulin levels to rise, and can cause blood glucose levels to rise if the pancreas is unable to produce enough insulin.
later on in the article they give it away by stating...
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Insulin sensitivity did not change.
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so the study made no difference to insulin resistance then? What, were they hoping that no one would notice that insulin senstivity and insulin resistance are the same?
