Going back to the original question about retinopathy progression and tight control. This article has some info on the mechanism.
Retinopathy progression
Theres a more reassuring graph with this label.
Quote:
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A 3% drop in HbA1c may increase the progression rate for 1-3 years. But after 3-4 years of good control, progression rates drops significantly (lilac line). In the long term, good control causes much less progression
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