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  #11 (permalink)  
Old 05-16-2008, 12:36 AM
Lizzie G Lizzie G is offline
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I am a: Type 1
 
Join Date: Jan 2008
Location: London UK
Posts: 244
Quote:
Originally Posted by lottadata View Post
Alice,

You're right.

The Lantus/Levemir head-to-head studies didn't show a dramatic difference the way the NPH study did.

But it's worth noting that the protocols for those Lantus/Levemir studies were all with people eating the extremely high carb diets and then using very high doses of insulin and achieving mediocre A1cs. When you are running high blood sugars and using huge doses of insulin you will gain weight. (Or at least, I will gain weight! That's been proven. <G>)

When people go for much tighter control and use less insulin the weight advantage may show up. I have heard from people who reported that happening when they switched.

It may simply be that because Leveimr is shorter acting it is possible to tailor the dose better and when you do that and keep blood sugars flatter, you end up not as hungry.

It's certainly worth a try if a person is gaining on Lantus.
I am really happy with Levemir and I gained a LOT of weight last winter when I started Lantus. Before that I'd been using R which was slow enough to lower my fasting bg too. When I switched to Lantus/Novolog even though my total daily dose was the same I managed to gain 5 lbs in little more than 6 weeks. I had not gained weight in several years before that.
interesting stuff. my TDD is pretty low (18 units max) due to training, pretty low carb and generally losing weight. of course all these factors have increased my daytime insulin sensitivity hugely which is whats caused the disparity in my basal needs.....for example...during the day 1/2 unit of novo can bring me down 2mmol (36 in US terms) whereas at night 1 unit can do NOTHING!
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