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  #12 (permalink)  
Old 06-18-2008, 06:20 AM
Eddy's Avatar
Eddy Eddy is offline
Senior Member
I am a: Type 1
 
Join Date: Jan 2008
Location: Kansas, US
Posts: 1,025
Re: Pre-D and T2 diet & exercise

Quote:
Originally Posted by BrianSCohen View Post
You migth start a separate thread on this.
Separate from the existing vitamin C thread?

Quote:
Originally Posted by BrianSCohen View Post
I was taking megadoses of vitamin C for some time, but feared that it might be having a negative effect. Linus Pauling was a big fan of it, and there is a bunch of studies that say it helps type 2 diabetics maintain diabetic control.
Interesting...

Quote:
Originally Posted by BrianSCohen View Post
There are however indications that for some it may have a bad impact as in High Doses of Vitamin C Supplement Increase Blood Glucose Levels - Diabetes Health.
Ascorbic acid and glucose are very similar molecules. Some meters are "confused" by vitamin C. Seeing how old the article is, and that it fails to mention the meter, I wish that I had more information. Were the readings artifacts? Does vitamin C indeed have the opposite effect in some to what it does in me? I wish that I knew...

Quote:
Originally Posted by BrianSCohen View Post
In my case, I have been concerned that various factors may be causing problems with my HbA1c test, which has been about 1% higher than might be expected given my average blood glucose levels.
What assay method was used for your A1c? Have you tried both with and without your vitamin C regimen?

Quote:
Originally Posted by BrianSCohen View Post
There seems to be a bunch of research that indicates that megadoses of vitamin C may adversely impact (ie. ruin) the HbA1c test as in Protein Glycation: Ascorbate Antagonism.
The final two paragraphs are badly written. They talk about how a "misleadingly low" A1c would be bad... yet, by their own prior admission:

"This suggests that the AA-associated lowering of GHb reflected a genuine in vivo decrease in glycation."

The objective is to prevent side effects from lots of sugar molecules being in the blood, and from lots of sugar molecules being stuck to proteins.

My observations are that vitamin C -- for me -- decreases the number of sugar molecules floating around. Other studies indicate that vitamin C decreases the number of sugar molecules stuck to the proteins.

Perhaps it's because I'm half-awake and running on three hours of sleep, but I'm arriving at a different conclusion than yours.
__________________
Eddy


DXed 2007/04 = advanced-stage DKA, A1c of 12.9%, and BMI of 21.3
post-DX A1c = 5.4% @ 2008/07; 5.2% @ 2008/04; 5.3% @ 2007/12; 5.3% @ 2007/08
c-peptide = 0.0% @ 2008/07
current BMI = 26.0 (86kg on 182cm); want to get back to 23-24
basal = 2U human N @ 0630, 5U detemir @ 0630, 11U detemir @ 1200, 17U detemir @ 2030
bolus = 1:15 I:C ratio; varying mix of aspart, human R, human N

not a low-CHO eater... not even close!
last updated 2008/08/18

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