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Originally Posted by BlueSky  All this could simply mean that, because of their genetic makeup, many people people don't become insulin resistant in spite of their lifestyles. The incidence of insulin resistance and T2 diabetes has increased too quickly over the last 30 years for for the explanation to be defective genes. The finding of the study in question makes pretty good sense to me.  |
Why not? How can you dismiss defective genes? Until there is a stressor on that gene, how would it manifest itself? And could the medical community identify it? I laugh at cops shows where they run a test on something and come up with some unique compound that is maybe specific to a small locality. Most test are run for specific things, not what is in it. Unless they suspected certain things, they never would have tested for them.
That could be the way it is for us. Our gene pool may all originate from one person a million year ago who gene went askew and passed it all down to us. It turned out that the offspring were prolific producers and whenever 2 "cousins" met up over the centuries, it became part of the our makeup, Thousands of years of dying from other things, made it hard to identify.
The current makeup of our world means we are living with the stressor that helps the manifestation. Plus medicine allows us to live long enough to reproduce, carrying the genes forward.
While different mutations may make us succeptable to type 1 or 2, the theory is still plausible. The industrial revolution a century ago may have been the trigger, it just takes longer in humans to exhibit symptoms because of our slow reproduction rate
