Maybe its just that I'm becoming more insulin sensitive who knows? The reason I suggested the cycles is that I remember finding a paper suggesting that people with LADA may have had several autoimmune 'attacks' during their lifetime with subsequent regeneration of beta cells culminating in losing too many and true insulin dependency. I 've been trying in vain to find that paper again.
Whilst searching I found a paper that suggested a) LADA should be renamed autoimmune diabetes in adults with slowly progressive Beta-cell failure
(ADASP)!
b) showed different rates of progression according to differing islet antibodies,
Quote:
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Patients with two or three antibodies had severely impaired beta-cell function (low to unmeasurable plasma C-peptide) after 5 years, whereas this occurred later (up to 12 years) among subjects with only ICAs or GADAs at diagnosis. Patients without islet antibodies or only IA-2As at diagnosis did not show decreases in plasma C-peptide after diagnosis during 12 years of observation
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Interestingly the accompanying graph showed a rise in c peptide at the 5 year mark for those with IA-2As and for GADAs.
Latent Autoimmune Diabetes in Adults: Definition, Prevalence, {beta}-Cell Function, and Treatment -- Stenstrm et al. 54 (Supplement 2): S68 -- Diabetes
