| Obesity is often the RESULT of insulin resistance, not the cause.
Studies of lean relatives of people with Type 2 found that they had much higher insulin resistance already than people whose relatives did not have Type 2.
Here are some other causes of insulin resistance:
1. Dropping Estrogen levels. When I go off estrogen supplementation I have to boost my insulin dose. If I go back on it, it drops.
2. Increasing age. Almost all older adults become more insulin resistant, probably because of wear and tear on receptors.
3. Abnormally high adrenal hormones. Cushings disease causes dramatically high IR. The body is pumping out natural cortisone and that causes IR.
4. Drugs, including Beta Blockers, Statins, and SSRI antidepressants. Many of the most commonly prescribed drugs our society has become addicted to raise insulin resistance, sometimes dramatically. Anti-psychotics can turn a normal person into a Type 2 diabetic, permanently in as little as a month.
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A1c 5.7% 10 years after diagnosis.
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