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Originally Posted by BlueSky Why should there be a difference? Insulin resistance is the inability of insulin to poke glucose into cells. Whether the insulin is naturally produced or injected is really besides the point. When animal insulins were used, incrementally increasing dosages was sometimes required because of autoimmune rejection problems. But this is not the case with modern "human" insulin. |
Actually there ARE differences in IR because there are many different CAUSES of IR.
A friend of mine recently saw her extremely high insulin need drop dramatically after she switched from analogs to humulin (R) insulin. Her receptors don't seem to have been able to process novolog.
Abnormalities of cortical hormones can also cause IR.
Some people become more IR with high fat intake while others become LESS IR.
The more scientists study diabetes the more all the sound-bite versions of how it works are biting the dust.