| When I first started on Metformin a number of years ago, I was originally on the 500 mg twice a day.
Eventually that wasn't enough to keep my numbers good. My doctor raised it to 1000 twice a day, then eventually added Glyburide and Actos over the next few years.
I'm currently on 850 mg of met 3x a day along with Glyburide AND now recently, insulin.
It could be that you need a larger dose or another med added to the mix to see results.
In my case, as I got older, (or the longer I was on them) the meds became less effective.
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Levemir, Novolog
Metformin 850 x 3
Lower carb lifestyle A1C:
11/3/07: 7.5
2/23/08: 7.4
8/30/08: 8.1  1/29/09: 5.7 5/21/09: 5.7 9/28/09: 5.8 Triglycerides:
11/3/07: 321
2/23/08: 328
8/30/08: 330 1/29/09: 166 5/29/09: 230
9/28/09: 201 | 
