| Off the top of my head, Novorapid and Humalog have been available since at least 1998, while Lantus hit the market in about 2001, and Levemir around 2003.
If you were on NPH and a bolus insulin then you already were on MDI, although as far as I know, NPH/Insulatard has been contraindicated since the arrival of Lantus. |