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  #10 (permalink)  
Old 02-09-2006, 10:50 AM
seacomp seacomp is offline
Senior Member
I am a: Type 2
 
Join Date: Feb 2006
Location: Virginia
Posts: 1,351
They did their best, but failed

The dosage problem with this are so bad that there really can be no question of it being used to replace injected insulin for those who need it. The dosage issue is probably worse than has been brought out, I would strongly suspect that there is a wide variation in the amount of insulin delivered per use for the same dose. That is when you take their 3 unit dose, you might get 2.2 units one time, 3.7 units the next, etc. As I said this is what I strongly suspect; I don't have any actual figures to back it up, but there are indications to this effect.
But in any case, these dosage problems are not deliberate. I'm sure that Pfizer would provide unit doses in a consistant manner, if they could. But they can't, it's in the nature of what they are trying to do that you can't get good dosage control.
Pfizer's error, and even more so the popular press's, is playing this up as a replacement for those painful "needle sticks". There is a potentially a very large role that inhaled insulin could play, but not where it's now positioned.
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