Hey, whatever works for you, but consider these things.
1. Not recommended by manufacturer. Hardly "odd" to follow these instructions.
2. Clinical trials indicate it does indeed affect the action of the insulin. Such as:
The early pharmacodynamic and pharmacokinetic effects of mixing lispro with glargine insulin: results of glucose clamp studies in youth with type 1 diabetes.
This is quite a recent study. I wonder if your endo is aware of it.Conclusion: These data demonstrate that mixing lispro with glargine markedly flattens the early pharmacodynamic peak of lispro and causes a shift to the right in the GIR curve changes that might lead to difficulties in controlling meal-related glucose excursions.