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08-31-2007, 11:22 AM
|  | Senior Member
I am a: Type 1 | | Join Date: Dec 2006 Location: Ontario, Canada
Posts: 1,496
| |  Faster Insulins?
To anyone's knowledge, are any companies out there actually working on faster insulins? Meaning, with a faster profile, peaking slightly earlier, and not lasting as long in the body?
If so, who? Any expected time frame for such a release?
__________________
Type 1
Dx'd Oct 2, 2006
Medtronic pumper - NovoRapid
Drusens in both eyes.
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08-31-2007, 11:40 AM
|  | Senior Member
I am a: Type 1 | | Join Date: Sep 2005 Location: Cincinnati, OH
Posts: 8,764
| | | I have not heard of any and all 3 major companies have a fast insulin out there. I think the major part of what slows it down is the fact that it has to go through fat. I know in trials with implantable pumps they have used R in them and they work almost just as fast as a non-diabetic. So the major issue to get by is dealing with fat.
__________________
●Blue Ash, Ohio Police Dispatcher
●Type 1 diabetic for 25 years (11 months old)
●Animas pumper since December of 2002
~IR 1000 (Dec. 2002 - Jan. 2005)
~IR 1200 (Jan. 2005 - Jan. 2009)
~Cozmo 1800 (Jan. 2009 - ?)
●Dexcom Seven+ since August 1, 2009 Diabetes is an Art, NOT a Science. You must master the control by skills and not by knowledge alone. |
08-31-2007, 11:43 AM
|  | Senior Member
I am a: Type 1 | | Join Date: Oct 2006
Posts: 1,325
| | I believe that Viaject is the most likely candidate to peak faster and clear from the body quicker.
__________________
MDI, Lantus and Novolog
A1c 10/09 -- 5.8%
A1c 4/09 -- 5.7%
A1c 10/08 -- 5.4%
A1c 4/08 -- 5.7%
A1c 8/07 -- 5.6%
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08-31-2007, 11:49 AM
| | Senior Member
I am a: Type 1 | | Join Date: Sep 2005 Location: Cincinnati, OH
Posts: 8,764
| | Quote:
Originally Posted by Scratch  I believe that Viaject is the most likely candidate to peak faster and clear from the body quicker. | Why oh why is everything always compared to R? That's what drives me nuts, heck, everything is faster than R. I hadn't heard of Viaject yet, interesting.
__________________
●Blue Ash, Ohio Police Dispatcher
●Type 1 diabetic for 25 years (11 months old)
●Animas pumper since December of 2002
~IR 1000 (Dec. 2002 - Jan. 2005)
~IR 1200 (Jan. 2005 - Jan. 2009)
~Cozmo 1800 (Jan. 2009 - ?)
●Dexcom Seven+ since August 1, 2009 Diabetes is an Art, NOT a Science. You must master the control by skills and not by knowledge alone. |
08-31-2007, 11:51 AM
| | Senior Member
I am a: Type 1 | | Join Date: Oct 2006
Posts: 1,325
| | Quote:
Originally Posted by JediSkipdogg Why oh why is everything always compared to R? That's what drives me nuts, heck, everything is faster than R. I hadn't heard of Viaject yet, interesting. | If you do a search for Viaject, you started a thread on it!
Yeah, it's hard to judge, but it's faster than R obviously, and looks to be slightly faster peaking and clearing than Huma/Novolog/Apidra analogues.
There also may be fewer concerns about mutagenic properties with the formulation as well.
__________________
MDI, Lantus and Novolog
A1c 10/09 -- 5.8%
A1c 4/09 -- 5.7%
A1c 10/08 -- 5.4%
A1c 4/08 -- 5.7%
A1c 8/07 -- 5.6%
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08-31-2007, 12:08 PM
| | Senior Member
I am a: Type 1 | | Join Date: Sep 2005 Location: Cincinnati, OH
Posts: 8,764
| | Quote:
Originally Posted by Scratch If you do a search for Viaject, you started a thread on it! | I did? LOL...musta been one I found by accident. I'm just use to paying attention to Eli Lilly, Novo Nordisk, and Aventis for insulins
__________________
●Blue Ash, Ohio Police Dispatcher
●Type 1 diabetic for 25 years (11 months old)
●Animas pumper since December of 2002
~IR 1000 (Dec. 2002 - Jan. 2005)
~IR 1200 (Jan. 2005 - Jan. 2009)
~Cozmo 1800 (Jan. 2009 - ?)
●Dexcom Seven+ since August 1, 2009 Diabetes is an Art, NOT a Science. You must master the control by skills and not by knowledge alone. |
08-31-2007, 12:34 PM
|  | Super Moderator
I am a: Type 1 | | Join Date: Aug 2003 Location: Northern California
Posts: 9,311
| | | Scratch can you explain a bit more on the "mutagenic properties" that they are concerned about? I looked online, but couldn't find anything. Do they mean mutagenic properties in mice or in the insulin itself?
__________________  Nancy Kind words can be short and easy to speak but their echoes are truly endless. Mother Teresa diagnosed type 1 October 1986
currently using Medtronic MiniMed
paradigm 715 CLEAR  |
08-31-2007, 12:49 PM
| | Senior Member
I am a: Type 1 | | Join Date: Oct 2006
Posts: 1,325
| | Quote:
Originally Posted by notme Scratch can you explain a bit more on the "mutagenic properties" that they are concerned about? I looked online, but couldn't find anything. Do they mean mutagenic properties in mice or in the insulin itself? | There are some concerns that the insulin analogs due to their structure may have mutagenic properties, that prolonged exposure may over time be cancer causing. The evidence isn't very clear so far as I can tell, and it's no guarantee that just because Viaject might have a "more natural" structure that it can't be mutagenic as well. Plenty of natural things can cause cancer too.
__________________
MDI, Lantus and Novolog
A1c 10/09 -- 5.8%
A1c 4/09 -- 5.7%
A1c 10/08 -- 5.4%
A1c 4/08 -- 5.7%
A1c 8/07 -- 5.6%
|
08-31-2007, 12:57 PM
| | Super Moderator
I am a: Type 1 | | Join Date: Aug 2003 Location: Northern California
Posts: 9,311
| | Thanks for the explaination. 
__________________ Nancy Kind words can be short and easy to speak but their echoes are truly endless. Mother Teresa diagnosed type 1 October 1986
currently using Medtronic MiniMed
paradigm 715 CLEAR |
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