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04-12-2008, 09:43 AM
|  | Senior Member
I am a: Type 1 | | Join Date: Jan 2008 Location: Kansas, US
Posts: 988
| | | difference between "A1c" and "glycated hemoglobin"?
While going through my time-of-DX hospital records, I noticed "glycated hemoglobin" of 19.0%. The reference range was <I forget the low end> to 7.8%, so it's apparently different than A1c... but I was even more over-the-top on that value.
Web searches tell me "glycated hemoglobin = A1c"... but the paperwork does not corroborate.
This perplexes me. Any thoughts?
__________________
Eddy
DXed 2007/04 = advanced-stage DKA, A1c of 12.9%, and BMI of 21.3
post-DX A1c = 5.4% @ 2008/07; 5.2% @ 2008/04; 5.3% @ 2007/12; 5.3% @ 2007/08
c-peptide = 0.0% @ 2008/07
current BMI = 26.0 (86kg on 182cm); want to get back to 23-24
basal = 2U human N @ 0630, 4U detemir @ 0630, 8U detemir @ 1130, 19U detemir @ 2030
bolus = 1:15 I:C ratio; varying mix of aspart, human R, human N
not a low-CHO eater... not even close!
last updated 2008/07/22
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04-12-2008, 09:55 AM
|  | Senior Member
I am a: Type 1 | | Join Date: Jun 2006 Location: Rothesay, New Brunswick Canada, eh
Posts: 6,372
| |
__________________ Michael Pollan on CBC
In Defense of Food with Michael Pollan T1 1975, MM 722 pump
A1C 7/08 5.9%
HDL - 1.55 (59.9)
LDL - 1.76 (68.1)
Triglicerides - 0.44 (40.0)
Called John, plus many other things
1 - - - - - - - - - - - - - - - - - - - - - - - - - - 3 - - - - - - - - - - - - - - - - - - - - - - - - - - 5  > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > >
John's Troll Meter - current level: Cold |
04-12-2008, 10:05 AM
| | Senior Member
I am a: Type 1 | | Join Date: Jan 2008 Location: Kansas, US
Posts: 988
| | Quote:
Originally Posted by xMenace  | Ehhh... I did the Google/Wikipedia thing already, looong before posting, and would tend to believe that... except one test showing 12.9% and another test showing 19.0%? That seems to be a bit of a divergence, even accounting for different methods...
__________________
Eddy
DXed 2007/04 = advanced-stage DKA, A1c of 12.9%, and BMI of 21.3
post-DX A1c = 5.4% @ 2008/07; 5.2% @ 2008/04; 5.3% @ 2007/12; 5.3% @ 2007/08
c-peptide = 0.0% @ 2008/07
current BMI = 26.0 (86kg on 182cm); want to get back to 23-24
basal = 2U human N @ 0630, 4U detemir @ 0630, 8U detemir @ 1130, 19U detemir @ 2030
bolus = 1:15 I:C ratio; varying mix of aspart, human R, human N
not a low-CHO eater... not even close!
last updated 2008/07/22
|
04-12-2008, 10:13 AM
| | Senior Member
I am a: Type 1 | | Join Date: Jun 2006 Location: Rothesay, New Brunswick Canada, eh
Posts: 6,372
| | Quote:
Originally Posted by Eddy Ehhh... I did the Google/Wikipedia thing already, looong before posting, and would tend to believe that... except one test showing 12.9% and another test showing 19.0%? That seems to be a bit of a divergence, even accounting for different methods... |
I hope you don't put 100% faith in any lab test. I sure don't. lab test errors - Google Search
__________________ Michael Pollan on CBC
In Defense of Food with Michael Pollan T1 1975, MM 722 pump
A1C 7/08 5.9%
HDL - 1.55 (59.9)
LDL - 1.76 (68.1)
Triglicerides - 0.44 (40.0)
Called John, plus many other things
1 - - - - - - - - - - - - - - - - - - - - - - - - - - 3 - - - - - - - - - - - - - - - - - - - - - - - - - - 5 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > >
John's Troll Meter - current level: Cold |
04-12-2008, 10:42 AM
| | Senior Member
I am a: Type 1 | | Join Date: Jan 2008 Location: Kansas, US
Posts: 988
| | Quote:
Originally Posted by xMenace | Nope.
But both tests were performed at the hospital, within 24 hours of one another. And 12.9 and 19.0 are very different numbers. And, again, the reference ranges differed significantly...
...so I wondered if anyone else had any clues. I thought that I might be overlooking something simple and obvious.
__________________
Eddy
DXed 2007/04 = advanced-stage DKA, A1c of 12.9%, and BMI of 21.3
post-DX A1c = 5.4% @ 2008/07; 5.2% @ 2008/04; 5.3% @ 2007/12; 5.3% @ 2007/08
c-peptide = 0.0% @ 2008/07
current BMI = 26.0 (86kg on 182cm); want to get back to 23-24
basal = 2U human N @ 0630, 4U detemir @ 0630, 8U detemir @ 1130, 19U detemir @ 2030
bolus = 1:15 I:C ratio; varying mix of aspart, human R, human N
not a low-CHO eater... not even close!
last updated 2008/07/22
|
04-12-2008, 03:08 PM
|  | Senior Member
I am a: Type 2 | | Join Date: Dec 2006 Location: South Dakota
Posts: 533
| | | There ARE 2 sets of numbers. One is a percentage, the other a raw number.
The percentage is what gets used.
__________________
If it is to be, it's up to me! -Lloyd
5/12/08 A1c 4.9 2/18/08 A1c 4.9 11/2007 A1c 5.3 8/2007 A1c 5.5 6/2007 A1c 5.7
3/2007 A1c 6.9 12/2006, A1c 7.8 9/2006, A1c 8.5 6/2006 A1c 8.7 |
04-12-2008, 03:31 PM
|  | Senior Member
I am a: Type 1 | | Join Date: Sep 2006 Location: Auckland, New Zealand
Posts: 1,875
| | | The only other test I know of is the fructosamine test, but I would have expected it to be referred to as a "glycated protein" test.
__________________
In my humble opinion  
Type1 since 1977
MDI using Lantus, Protophane, Novorapid and Actrapid
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04-12-2008, 04:00 PM
| | Senior Member
I am a: Type 1 | | Join Date: Jan 2008 Location: Kansas, US
Posts: 988
| | Quote:
Originally Posted by Lloyd There ARE 2 sets of numbers. One is a percentage, the other a raw number. | I thought both numbers were expressed as percentages. (Where did I put that packet?) Quote:
Originally Posted by BlueSky The only other test I know of is the fructosamine test, but I would have expected it to be referred to as a "glycated protein" test. | I'm certain that it said "hemoglobin".
I'll dig out the packet, reread to see if I'm in error about percentage/"hemoglobin", and take it from there. Thanks for the leads, guys! 
__________________
Eddy
DXed 2007/04 = advanced-stage DKA, A1c of 12.9%, and BMI of 21.3
post-DX A1c = 5.4% @ 2008/07; 5.2% @ 2008/04; 5.3% @ 2007/12; 5.3% @ 2007/08
c-peptide = 0.0% @ 2008/07
current BMI = 26.0 (86kg on 182cm); want to get back to 23-24
basal = 2U human N @ 0630, 4U detemir @ 0630, 8U detemir @ 1130, 19U detemir @ 2030
bolus = 1:15 I:C ratio; varying mix of aspart, human R, human N
not a low-CHO eater... not even close!
last updated 2008/07/22
|
04-12-2008, 10:02 PM
| | Senior Member
I am a: Type 1 | | Join Date: Jan 2008 Location: Kansas, US
Posts: 988
| | I wonder if both numbers were indeed A1c tests, performed via different methods.
I should mention that, during the two months prior to DX, I'd been taking large quantities of vitamin C -- 55-80 g/day, with 65 g/day on average. Perhaps the high ascorbic acid consumption affected different tests differently. Vitamin C, glycation, glycohemoglobin and aging
Or, maybe it was what Lloyd said. Where did I put that packet?
__________________
Eddy
DXed 2007/04 = advanced-stage DKA, A1c of 12.9%, and BMI of 21.3
post-DX A1c = 5.4% @ 2008/07; 5.2% @ 2008/04; 5.3% @ 2007/12; 5.3% @ 2007/08
c-peptide = 0.0% @ 2008/07
current BMI = 26.0 (86kg on 182cm); want to get back to 23-24
basal = 2U human N @ 0630, 4U detemir @ 0630, 8U detemir @ 1130, 19U detemir @ 2030
bolus = 1:15 I:C ratio; varying mix of aspart, human R, human N
not a low-CHO eater... not even close!
last updated 2008/07/22
|
04-14-2008, 07:43 PM
|  | Senior Member
I am a: Type 2 | | Join Date: Aug 2004 Location: Mind -Langhorne PA Heart - The Shenandoah Valley
Posts: 635
| | | There are several types of hemoglobin in a red blood cell. The glycosylated Hemoglobin measures how much sugar is stuck to all of The different kinds of hemoglobin in a red blood cell while the hemoglobin A1c measures how much sugar is stuck to a particular kind of hemoglobin - hemoglobin A1. The normal range for the A1C is about 2% lower then the total glycosylated Hemoglobin Levels.
__________________
Byetta 5mcg twice a day
Sugar busters life style
Exercise = cardio and running after twins Ben & Josh
"Oh for Pete's sake" -Ben "Let me think" - Josh
Ok Wildcards watch your six.
You too will be assimilated! You will become one with the Borg. You will all become one with the borg."
To lose this war means more than defeat. To surrender is to never go home. All of us must rise to the call above and beyond". Lt Col TC McQueen  |
04-14-2008, 08:55 PM
| | Senior Member
I am a: Type 1 | | Join Date: Jan 2008 Location: Kansas, US
Posts: 988
| | Quote:
Originally Posted by jacobsam622 There are several types of hemoglobin in a red blood cell. The glycosylated Hemoglobin measures how much sugar is stuck to all of The different kinds of hemoglobin in a red blood cell while the hemoglobin A1c measures how much sugar is stuck to a particular kind of hemoglobin - hemoglobin A1. The normal range for the A1C is about 2% lower then the total glycosylated Hemoglobin Levels. | This meshes well, considering that the top end of the "glycated hemoglobin" range was 7.8% -- which is indeed about two percentage points above the top end of the A1c range.
Thanks.
__________________
Eddy
DXed 2007/04 = advanced-stage DKA, A1c of 12.9%, and BMI of 21.3
post-DX A1c = 5.4% @ 2008/07; 5.2% @ 2008/04; 5.3% @ 2007/12; 5.3% @ 2007/08
c-peptide = 0.0% @ 2008/07
current BMI = 26.0 (86kg on 182cm); want to get back to 23-24
basal = 2U human N @ 0630, 4U detemir @ 0630, 8U detemir @ 1130, 19U detemir @ 2030
bolus = 1:15 I:C ratio; varying mix of aspart, human R, human N
not a low-CHO eater... not even close!
last updated 2008/07/22
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