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02-20-2006, 03:12 AM
| | Administrator
I am a: Type 1 | | Join Date: Feb 2002 Location: Rhode Island
Posts: 4,158
| | | Diabetes reversed in monkeys
Researchers at the University of Minnesota announced Sunday that they were able to reverse diabetes in monkeys by transplanting insulin-producing cells from pigs. More info here.
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Tony
Administrator of Diabetesforums.com "Weeding my way through Diabetes, and taking all of you along for the ride." - archimeech |
02-20-2006, 03:33 AM
|  | Senior Member
I am a: Type 1 | | Join Date: Sep 2005 Location: Cincinnati, OH
Posts: 8,244
| | | I read about that and that's pretty cool. I found some more info on it somewhere else and they say some of the monkeys are on no anti-rejection drugs. The biggest problem still is creating islet cells. They say you can only get 1 islet cell from a healthy pancreas. With over 20 million diabetics in the US, that's alot of islet cells needed and you have to hope they aren't rejected.
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●Blue Ash, Ohio Police Dispatcher
●Type 1 diabetic for 25 years (11 months old)
●Animas pumper since December of 2002
~IR 1000 (Dec. 2002-Jan. 2005)
~IR 1200 (Jan. 2005 - ?)
●LifeScan OneTouch UltraSmart Diabetes is an Art, NOT a Science. You must master the control by skills and not by knowledge alone. |
02-20-2006, 05:04 AM
|  | Senior Member
I am a: Type 1.5 | | Join Date: Feb 2006 Location: Orlando, FL
Posts: 7,833
| | | They are already implanting islet cells in humans in clinical trials. |
02-20-2006, 05:09 AM
| | Senior Member
I am a: Type 1 | | Join Date: Sep 2005 Location: Cincinnati, OH
Posts: 8,244
| | Quote: |
Originally Posted by Cyborg They are already implanting islet cells in humans in clinical trials. | But for the human versions anti-rejection drugs are being taken. So one is supplementing insulin with an anti-rejection drug. In the Monkey/Pig experiment they are actually finding that no anti-rejection drugs are needed. In the majority of their trials, the body has not re-attacked the islet cells, only a small percentage have had to go back on insulin, the rest are drug free.
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●Blue Ash, Ohio Police Dispatcher
●Type 1 diabetic for 25 years (11 months old)
●Animas pumper since December of 2002
~IR 1000 (Dec. 2002-Jan. 2005)
~IR 1200 (Jan. 2005 - ?)
●LifeScan OneTouch UltraSmart Diabetes is an Art, NOT a Science. You must master the control by skills and not by knowledge alone. |
02-20-2006, 05:15 AM
| | Senior Member
I am a: Type 1.5 | | Join Date: Feb 2006 Location: Orlando, FL
Posts: 7,833
| | | Without going into politics and/or religeon, once they perfect the procedure and then transfer the technology to humans, all we need is stem cell research as the last link (forget the pancreas donations). Wow! That is promising.
I knew about the rejections in humans and the anti-rejection drugs people had to take. I did not know about the monkey trials. Anyone got a link to more info? |
02-20-2006, 06:12 AM
|  | Senior Member | | Join Date: Oct 2003 Location: Manassas, in the Old Dominion
Posts: 6,517
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Last edited by Harold : 02-20-2006 at 11:20 AM.
Reason: asked for smilies
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02-20-2006, 06:18 AM
| | Senior Member | | Join Date: Oct 2003 Location: Manassas, in the Old Dominion
Posts: 6,517
| | Eeesh, I "sound" mean. Someone put some smilies in my previous post, please.  |
02-20-2006, 06:56 AM
| | Senior Member
I am a: Type 1.5 | | Join Date: Feb 2006 Location: Orlando, FL
Posts: 7,833
| | | I didn't mean to imply that stem cells were the only way to go. It just seems to me that it is a good way to replicate or mass produce the needed islet cells needed to cure a diabetic. Cloning has gotten such a bad rep and now stem cell is getting one before it is getting a fair chance. I'm not for or against stem cell research. I just want a cure for diabetes, period. I don't care how they get the cure. |
02-22-2006, 07:31 AM
| | Member
I am a: Type 1.5 | | Join Date: Feb 2006 Location: Canada
Posts: 140
| | I live in Edmonton, Canada, and they are already doing islet cell transplants here. http://www.diabetes.org.uk/islets/trans/edmonton.htm
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-Rea
1.5 taking Levemir, and Humalog
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02-22-2006, 09:58 AM
|  | Senior Member
I am a: Type 1 | | Join Date: Oct 2005 Location: Sacramento California
Posts: 2,503
| | Quote: |
Originally Posted by duck Why is it that everyone seems to think the cure to everything is in stem cells? | Because they have the ability to become any cell in the body. Replacing damaged or lost cells and most importantly the nucleus in the stem cells is identical to every other cell in the body. Quote: |
Originally Posted by Cyborg Cloning has gotten such a bad rep and now stem cell is getting one before it is getting a fair chance. | Stem cell research isn't getting a bad rep, it's the way they are collected in which the debate arises. Embroyonic stem cell research, in which the stem cells are collected from human embryos, will hold the same arguement that abortion does. I don't believe embryonic stem cell research hold the answers because the stem cells are from a donor and are not identidied as 'self' when in a new host. Scientist can transplant nuclei from the patient(new host) to the embryonic stem cells to trick the new host into thinking they are 'self' but this is a very, VERY cumbersome process and often very unsuccessfull. IMO Adult stem cells are where the answers lie, and are not subject to much debate, other than if you want to clone someone with the adult stem cell. These cells are collected from adult patients. That's where the name for the Edmonton Protocol came from! DoH, I always wonder how it got that name. Canada has done so much for diabetes treatment/research. Pretty cool.
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I have seen this article all over the news threads yesterday and today, and don't see how it is that big of news. Scientists having been doing stuff like this since the 80's. I guess they are just getting better at it. This latest news threads technology is way behind www.microislet.com technology. We need to gather all the top scientists and get them on the same page. Anyone have a couple of million for it? 
Last edited by BriOnH : 02-22-2006 at 10:03 AM.
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02-22-2006, 03:22 PM
| | Senior Member
I am a: Type 1.5 | | Join Date: Feb 2006 Location: Orlando, FL
Posts: 7,833
| | | I'm sure the diabetes pump, supply and drug companies have the money required, but that would hurt their profits! |
02-22-2006, 03:27 PM
| | Senior Member | | Join Date: Oct 2003 Location: Manassas, in the Old Dominion
Posts: 6,517
| | Quote: |
Originally Posted by Cyborg I'm sure the diabetes pump, supply and drug companies have the money required, but that would hurt their profits! | Did someone just summon me for a conspiracy theory?
LOL
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I'll mend myself before it gets me... |
02-22-2006, 03:47 PM
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I am a: Type 1.5 | | Join Date: Feb 2006 Location: Orlando, FL
Posts: 7,833
| | 
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02-22-2006, 04:05 PM
| | Senior Member | | Join Date: Oct 2003 Location: Manassas, in the Old Dominion
Posts: 6,517
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Originally Posted by Cyborg
. | I'm just kidding, though I have heard conspiracy theories on the dozens of diseases where the cure exists, but the powers-that-be have sat on that information in order to make a profit selling drugs to those who have said diseases...If they don't die, they make someone money. If they die, they don't make you money. And if they are cured, they stop buying your drugs, and you make no money. So sit on the cure.
Wait...Now that I say that...Hmmmmmmmmmmmmmmmm... 
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I'll mend myself before it gets me... |
02-22-2006, 04:32 PM
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__________________  Rest In Peace Jack- 5/1/08. You may be gone from us but you will never be forgotten. Our love goes with you. |
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Not picking on you, Cyborg, you were just the first to say it. Here we have a study that says they reversed diabetes in monkeys without stem cells, YET the next leap is to think we need stem cells for a human treatment? 
