Type 1.5, Please Explain

[gobbly2100]

I have had type 1 diabetes for 8 years but have never heard of type 1.5, what is that?

[sweetcheeks]

Type 1.5 Diabetes
aka Slow Onset Type 1 and LADA
Type 1.5 is one of several names now applied to those who are diagnosed with diabetes as adults, but who do not immediately require insulin for treatment, are often not overweight, and have little or no resistance to insulin. When special lab tests are done, they are found to have antibodies, especially GAD65 antibodies, that attack their beta cells. This sort of diabetes is sometimes called Slow Onset Type 1 or Latent Autoimmune Diabetes in Adults or LADA.

Diabetes Types, Type 1.5, Slow Onset Type 1 and LADA. (http://www.diabetesnet.com/diabetes_types/diabetes_type_15.php)

[gobbly2100]

Will it eventuarly become type 1 diabetes then right?

[sweetcheeks]

i dunno im confused myself about it, i think type 1.5 is a mixture of both type 1 and type 2 is kinda how i take it, someone correct me if im wrong please

[Funnygrl]

There are two types of diabetes generally labeled at type 1.5. The first is LADA, and that is accurately called type 1.5. The second is MODY, which some say is a misnomer to call type 1.5.

LADA stands for latent autoimmune diabetes of adults. It is basically an autoimmune form of diabetes that effects older people and takes longer to set in. It's just like type 1 diabetes in that it can't be prevented and requires insulin to manage eventually, though this can take awhile. This is most likely where I am, and I was on insulin 4 months after diagnosis. It can take up to 10 years though.

MODY stands for Maturity Onset Diabetes of Youth. This is a rare genetic condition that usually does not require insulin, but is not preventable as well.

Neither condition typically involves insulin resistance.

[Funnygrl]

Will it eventuarly become type 1 diabetes then right?
LADA is a subtype of type 1, and will eventually be identical to classic type 1 diabetes.

[Kimber]

I was diagnosed in Dec as type 2 but they have decided 3 weeks ago that I am really type 1.5 and Immediately put me on insulin. Though my pancrease is giving its last dying gasp, it is still producing a tiny bit of insulin (2 on the last test while BG was 300) Type 1.5 is also called "double diabetes" because I am insulin dependent (soon to have no production at all) as well as insulin resistence (both types at once, oh boy).
Kimber

[grace girl]

I don't even think the doctors have a handle on it. I was dx'ed type 1 at age 32, almost 7 years ago. Last year a new endo decided it was really 1.5 because of my age at dx. (I have no insulin resistance) My current endo told me, no, it's really type 1.

Who know??

[Rebecca]

I was diagnosed in Dec as type 2 but they have decided 3 weeks ago that I am really type 1.5 and Immediately put me on insulin. Though my pancrease is giving its last dying gasp, it is still producing a tiny bit of insulin (2 on the last test while BG was 300) Type 1.5 is also called "double diabetes" because I am insulin dependent (soon to have no production at all) as well as insulin resistence (both types at once, oh boy).
Kimber

Like stated before TYPE 1.5 is a SLOW ONSET VERSION OF TYPE 1 DIABETES.
DOUBLE DIABETES is when one has TYPE 1 FIRST, and then subsequently has signs and symptoms of TYPE 2. Double diabetes is diagnosed in those that ALREADY HAVE TYPE 1 diabetes, but also have the INSULIN RESISTANCE of type 2.
To have DOUBLE DIABETES, one must be a TYPE 1 and then insulin resistance ontop of that.. basicall PRODUCE ZERO insulin for years, and then becomes RESISTANT to the INJECTED insulin.... Happens mostly in those that are PREDISPOSED TO TYPE 2 DIABETES MELLITUS.
Double diabetes is a DIAGNOSIS ON ITS OWN.. NOT A DIAGNOSES OF DIABETES ITSELF.
TYPE 1.5 is also known as Latent Autoimmune Diabetes of the Adult aka LADA (over a period of YEARS)
TYPE 1 is automatic (over a period of days/weeks) destruction of the pancreatic beta cells in addition to the alpha and delta cells of the islets of langerhans
TYPE 2 is when your body does not effectively use or produce insulin, in reguards to your body effectively needs to transport glucose (from the food you eat) into the cells. Hence the reasons for sulfonureas (eg. Gliburide, glucatrol) aka medications to force your pancreas to produce more insulin, Biguanides (eg Metformin aka glucaphage, ect) or similar, which prevents your liver from producing the glucose that it does make, and then the insulin sensitizers (eg actos, avandia), which target your muscle cells to be sensitive to the insulin you already make.
DOUBLE DIABETES, IS THE DIAGNOSIS OF TYPE 1 FIRST THEN THE INSULIN RESISTANCE OF TYPE 2 OR BOTH TYPE 1 AND TYPE 2.
DOUBLE DIABETES IS A NEW DIAGNOSIS (last 5 years) THAT THE MEDICAL PROFESSIONALS HAVE CAME UP WITH FOR THOSE THAT ARE ORIGINALLY DIAGNOSED WITH TYPE 1 THEN BECOME RESISTANT TO THE INSULIN THAT THEY DO PRODUCE

[BlueSky]

If only the medical profession would get their terminology sorted out! I have also seen so-called Double Diabetes (Insulin resistant T1s) referred to as Type 3 diabetes. They really should be using more descriptive names, like Autoimmune Diabetes(T1) and Insulin Resistant Diabetes(T2). In which case the meaning of Double Diabetes would be a lot clearer.

[NoraWI]

Type 3 diabetes is what they have begun calling Alzheimer's Disease, which can be a complication of long term uncontrolled diabetes. Yes, I, too, wish the medical profession would sort out their nomenclatures. Unfortunately, they haven't really sorted out their understanding of DM and its various types as yet. Not many out there like Rebecca above (a Fellow of Paediatric Endocrinology).

[Kimber]

Rebecca,
I am coming up on another visit to my endo and will call for clarification on the labels. She has me currently labeled as 1.5 but my whole diagnosis came up in a matter of 6 weeks and very strong. I went in 6 weeks from 20/20 vision to not legal to drive with BG readings of 480 and insulin levels of 2. HBA1C was at 14. Apparently this does not fit with "slow onset" description of 1.5. I will let her know. It sounds like a better term for me is "double diabetes" even though it all happened at once. My endo says that I am (from test results) both GAD antibody positive (type 1 auto immune disorder) and resistent to effective use of insulin (and so am on metformin and Actose). I don't know if they happened consecutively or sequentially but that is where I am now and it was all discovered in Dec. The last 4 months have been, "how to treat it?"
Kimber

[owlyn]

I was (mis)diagnosed at age 40 as T2, but in less than a year, I asked to be put on insulin (having lost 55 pounds (187 to 133)). I consider myself Type 1, just late onset. My c-peptide level is undetectable.

At least I know I didn't have it long before diagnosis. 6 months earlier, my A1C was suspicious 5.9, I think), and my triglycerides were high. Doctor said we should keep an eye on it. I was what is now known as pre-diabetec. 6 months later it was official.

[shabbie6247]

correct me if i'm wrong anybody, but my understanding of it is this

Latent Auto-immune Diabetes in Adults / LADA/type 1.5

is actually type one but it has lain dormant since birth (hence the term LATENT), so it has been dormant until such a time as a virus or something has triggered it to become active?:sheep: