dgrilli
01-15-2007, 02:59 PM
Symptoms of overt biotin deficiency include hair loss and a scaly red rash around the eyes, nose, mouth, and genital area. Neurologic symptoms in adults have included depression, lethargy, hallucination, and numbness and tingling of the extremities. The characteristic facial rash, together with an unusual facial fat distribution, have been termed the "biotin deficient face" by some experts (7). Individuals with hereditary disorders of biotin metabolism resulting in functional biotin deficiency have evidence of impaired immune system function, including increased susceptibility to bacterial and fungal infections (8).
I have noticed this rash exactly where this paragraph says. Also the Lethargy (Lazyness) I could never figure out why I always had this red rash around my nose into my cheeks that would scale over then start all over again.
Diabetes mellitus
It has been known for many years that overt biotin deficiency results in impaired utilization of glucose (13). Blood biotin levels were significantly lower in 43 patients with non-insulin dependent diabetes mellitus (NIDDM) than in non-diabetic control subjects, and lower fasting blood glucose levels were associated with higher blood biotin levels. After one month of biotin supplementation (9 mg/day) fasting blood glucose levels decreased by an average of 45% (14). Reductions in blood glucose levels were also found in 7 insulin-dependent diabetics after 1 week of supplementation with 16 mg of biotin daily (15). Several mechanisms could explain the glucose-lowering effect of biotin. As a cofactor of enzymes required for fatty acid synthesis, biotin may increase the utilization of glucose to synthesize fats. Biotin has been found to stimulate glucokinase, an enzyme in the liver, resulting in increased synthesis of glycogen, the storage form of glucose. Biotin has also been found to stimulate the secretion of insulin in the pancreas of rats, which also has the effect of lowering blood glucose (16). An effect on cellular glucose (GLUT) transporters is also currently under investigation. Presently, studies of the effect of supplemental biotin on blood glucose levels in humans are extremely limited, but they highlight the need for further research.
I'm taking for the 5th day a substance called Insulow that some here posted. This contains 100mg of R-ALA and 750mcg of Biotin.
If you want to read the Articles they are at the Linus Pauline Institute.
Linus Pauling Institute at Oregon State University (http://lpi.oregonstate.edu/infocenter/vitamins/biotin/)
Linus Pauling Institute at Oregon State University (http://lpi.oregonstate.edu/infocenter/othernuts/la/#metabolism)
This was a truly Lookie what I found about Biotin. I did it out of Boardom and I'm glad I have.
We will see if this face red rash goes away that I have had for years.
I have noticed this rash exactly where this paragraph says. Also the Lethargy (Lazyness) I could never figure out why I always had this red rash around my nose into my cheeks that would scale over then start all over again.
Diabetes mellitus
It has been known for many years that overt biotin deficiency results in impaired utilization of glucose (13). Blood biotin levels were significantly lower in 43 patients with non-insulin dependent diabetes mellitus (NIDDM) than in non-diabetic control subjects, and lower fasting blood glucose levels were associated with higher blood biotin levels. After one month of biotin supplementation (9 mg/day) fasting blood glucose levels decreased by an average of 45% (14). Reductions in blood glucose levels were also found in 7 insulin-dependent diabetics after 1 week of supplementation with 16 mg of biotin daily (15). Several mechanisms could explain the glucose-lowering effect of biotin. As a cofactor of enzymes required for fatty acid synthesis, biotin may increase the utilization of glucose to synthesize fats. Biotin has been found to stimulate glucokinase, an enzyme in the liver, resulting in increased synthesis of glycogen, the storage form of glucose. Biotin has also been found to stimulate the secretion of insulin in the pancreas of rats, which also has the effect of lowering blood glucose (16). An effect on cellular glucose (GLUT) transporters is also currently under investigation. Presently, studies of the effect of supplemental biotin on blood glucose levels in humans are extremely limited, but they highlight the need for further research.
I'm taking for the 5th day a substance called Insulow that some here posted. This contains 100mg of R-ALA and 750mcg of Biotin.
If you want to read the Articles they are at the Linus Pauline Institute.
Linus Pauling Institute at Oregon State University (http://lpi.oregonstate.edu/infocenter/vitamins/biotin/)
Linus Pauling Institute at Oregon State University (http://lpi.oregonstate.edu/infocenter/othernuts/la/#metabolism)
This was a truly Lookie what I found about Biotin. I did it out of Boardom and I'm glad I have.
We will see if this face red rash goes away that I have had for years.