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View Full Version : Lantus users that HAVEN'T gone low?


Scarlett
05-09-2007, 11:13 AM
Just about every thread that I've been reading here have all mentioned many lows with the use of Lantus....are there any "users" out there that do not experience that many?
Hate to say this... but my BS's just about every morning are between 45-80. When I lower my PM dose...the next AM...I'm over 200's??? I just stick with the 15U at night and try to eat very little before bed. (If I eat...my sugars are in the basement.) Confusion has been my constant state of mind with trying to figure out this disease.:confused:

Opal
05-09-2007, 11:18 AM
I haven't had any problems with Lantus sending me low (to my knowledge), they've all been the result of me not working out how much insulin to take correctly or leaving food too late!

cheryl
05-09-2007, 11:24 AM
That started to happen to me once I lowered the lantus to a certain level everytime I lowered it more i was high the next morning the key is too let it sink in your system for three to four days, like the first day you will be high and probably the second, after that it should start leveling off if it is the right dose, I did that and it started to work, better for me, then instead I started to deal with low's all day long lol.....sometime depending on activity and just remember lantus has a 30% absorbtion rate each and every time you take it so that is a lot to take into consideration....

Cheryl

sofaraway
05-09-2007, 11:24 AM
I haven't had any problems with Lantus sending me low (to my knowledge), they've all been the result of me not working out how much insulin to take correctly or leaving food too late!

Sounds like you could be taking too much lantus if you have to eat to prevent going low.

For me i can stay steady between 4-6 mmol all day until 6-7pm if i don't eat anything. the only time i occasionally go low from basal insulin is if i am significantly more active and don't eat anything to compensate

Lloyd
05-09-2007, 12:07 PM
[QUOTE=Scarlett;221255]Just about every thread that I've been reading here have all mentioned many lows with the use of Lantus....are there any "users" out there that do not experience that many?
QUOTE]

I used lantus for 2 months and did not have one single low.
That is because I was always high, only on rare occasions did my fasting glucose go below 180.
I was on 99 units.
So for me, Lantus was a total failure, it just didn't work.

-Lloyd

Dervish
05-09-2007, 06:18 PM
When I was first dxed, I got sent home from the hospital with instructions to take 80 units of Lantus daily and I was having multiple mild hypos every day. Once I talked to a doctor about that and got the dose reduced, it got much better and I've been averaging one hypo every week or two since that, although I tend to be pretty high 2 hours after breakfast and dinner.

I'm not sure whether you'd consider that to be "many lows" or not, but it's another data point for you...

NoraWI
05-09-2007, 07:57 PM
If you go low a lot and wake up high then Lantus probably does NOT last 24 hours for you and you might try splitting the dose.

Just_Plain_John
05-10-2007, 07:25 AM
I take my Lantus before bed and do not have lows in the AM (nor overnight, when I was first starting I tested at 3AM for a week). My morning readings do fluctuate some from mid 80s to almost 120, but that seems to be related more to my bedtime snack. When I can avoid that snack, my AM reading is consistent 85-99.

PinCushion
05-12-2007, 03:04 AM
Hi there. Not sure how long ago you posted this, I'm new to the whole forum thing (my husbands idea). I hated lantis. I was on it for about 3 years, suddenly about 4 months ago I started having the same problem as you. Doctor said "somestimes our bodies just change the way they obsorb things" So he switched me to Levomir, I love it. However, it is twice a day and not once. I am taking ten units in the AM and ten units in the PM. No more lows (isn't it th worst when that's what you wake up to in the morning???) and I can tell a definite improvement in my bg's throughout the day.

lgvincent
05-12-2007, 08:49 AM
I hate to hear of the problems with Lantus. I'm on my last vial of NPH now and getting ready to switch to it. I was hoping for fewer insulin reactions when I made the switch.

BriOnH
05-12-2007, 11:25 AM
I hate to hear of the problems with Lantus. I'm on my last vial of NPH now and getting ready to switch to it. I was hoping for fewer insulin reactions when I made the switch.

You will. I gurantee it.

With any insulin you can go low. You just have to fine tune it. I do not experience lows from lantus. I always experience them from novolog.

Nita
05-12-2007, 01:56 PM
I just don't know about me.......:( I am on Levemir, am a type 2 and last night took my usual 39 units at 8:30...woke up this morning at 5 with a fasting of 124, had coffee, took it again at 7:30 reading 156. I hear some say coffee might raise blood sugar but shouldn't the Levemir have kept it from going up 30 points? I do bolus Humalog before meals.

Nita

BlueSky
05-12-2007, 02:43 PM
.... shouldn't the Levemir have kept it from going up 30 points? I do bolus Humalog before meals.

Nita
Nita,

Looks like you have a lot of insulin resistance, which accentuates the Dawn Phenomenon effect. And, no, Levimer won't stop it from happening. If this morning BG rise is a repeating pattern, you may want to consider replacing the bedtime Levimer with NPH. The peak in it should deal with the DP blood glucose rise.

BriOnH
05-12-2007, 08:32 PM
Looks like you have a lot of insulin resistance, which accentuates the Dawn Phenomenon effect.

Why would you 'diagnose' insulin resistance from that statement?

Funnygrl
05-12-2007, 08:38 PM
Why would you 'diagnose' insulin resistance from that statement?
Probably based on the part that said, "I am a type 2." Which, iirc, basically means insulin resistance.

Going back to the original question, lows are a fact of life with type 1. There's no insulin regimen that is guranteed to prevent them.

BlueSky
05-13-2007, 04:56 AM
Why would you 'diagnose' insulin resistance from that statement?
39 units of basal and an insulin:carb bolus ratio of 1:5 (see http://www.diabetesforums.com/forum/type-2/18350-my-a1c-my-disappointment.html#post219027)is a lot of insulin. It is because of insulin resistance that so much inulin is required to keep BG down.

Nita
05-13-2007, 06:28 AM
39 units of basal and an insulin:carb bolus ratio of 1:5 (see http://www.diabetesforums.com/forum/type-2/18350-my-a1c-my-disappointment.html#post219027)is a lot of insulin. It is because of insulin resistance that so much inulin is required to keep BG down.

This is one more good reason I am coming here to read....y'all are teaching me more about myself than I could ever learn when I WANT TO KNOW instead of waiting for the three month visit to the endo. I guess I am super insulin resistant and probably need to cut more carbs. Boo ... Hiss !

Even being a type 2 I still read much of the type 1 threads as we take so much of the same meds.

Thanks to all of you,
Nita

REDLAN
05-13-2007, 06:59 AM
I'm on levemir, not lantus, and I get the problem that the difference between waking up high or low in the morning is around 2 units...

14 units of levemir at night wake up with 3.7 (67), try 12 units of Levemir wake up with 13.3 (240).

seems to be the same kind of problem a couple of others have posted on this thread.

I have no idea why there should be such a sensitivity.

I find that I constantly have to adjust my basals last week I was on 12 units at night and still dropping low in the morning, and was thinking about dropping it to 10 units, AND this week I'm on 14 and just about holding below 10 (180) - I think it's the weather - last week was sunny - this week is rainy and I'm indoors more.

BlueSky
05-13-2007, 12:35 PM
Redlan,

Finding the right dose of Lantus is tricky if you are sensitive to insulin. I overcame this problem by splitting the dose. In addition to bridging a gap in action duration, splitting the dose reduces variability in action intensity and duration. It also evens out the action profile, which is not as flat as Lantus marketing suggests. I now get consistently good results from injecting 6 units in the morning and 6 units before bed.

DanG
05-14-2007, 09:12 PM
Hate to say this... but my BS's just about every morning are between 45-80.

I quit doing evening lantus when I had the parameds here at 3am.

I do lantus in the morning - no more lows in the early morning, no paramedics over here because of hypo. I tried the split, and the paramedics came to visit - that was the end of that experiment. I may do the split again sometime, but not for now, as the lantus in the morning does me fine.