wiseguy
06-29-2007, 10:34 PM
Quoted from The Diabetes Blog (http://www.thediabetesblog.com/2007/06/27/three-year-byetta-study-positively-a-joke/)
Byetta-makers Amylin and Lilly visited the American Diabetes Association's annual meeting and released clinical results from a three-year trial, the lengthiest one to date. The 217 patients with diabetes enrolled in the study had poor blood glucose control with other diabetes drugs metformin or sulfonylurea. Byetta was added to the mix.
Here's the punchline -- after three years, 46 percent of patients were able to maintain blood-glucose levels of a 7.0 A1C (not impressive for a type 2 diabetic) and 30 percent had a 6.5 A1C -- the target level recommended by the ACE Diabetes Mellitus Consensus Conference in 2001. Notice the media reports do not say anything about the remaining 24 percent who obviously had A1C levels higher than 7.0. Add that 24 percent to the 46 percent at the non-optimal level of 7.0 A1C and you get 70 percent of patients maintaining blood sugars high enough over three years to silently develop retinopathy, kidney problems and nerve damage, to name a few.
Byetta-makers Amylin and Lilly visited the American Diabetes Association's annual meeting and released clinical results from a three-year trial, the lengthiest one to date. The 217 patients with diabetes enrolled in the study had poor blood glucose control with other diabetes drugs metformin or sulfonylurea. Byetta was added to the mix.
Here's the punchline -- after three years, 46 percent of patients were able to maintain blood-glucose levels of a 7.0 A1C (not impressive for a type 2 diabetic) and 30 percent had a 6.5 A1C -- the target level recommended by the ACE Diabetes Mellitus Consensus Conference in 2001. Notice the media reports do not say anything about the remaining 24 percent who obviously had A1C levels higher than 7.0. Add that 24 percent to the 46 percent at the non-optimal level of 7.0 A1C and you get 70 percent of patients maintaining blood sugars high enough over three years to silently develop retinopathy, kidney problems and nerve damage, to name a few.