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miss_ok_ish
11-23-2007, 03:13 PM
sorry guys but i'm 28 and was dx'd only in june, they thought i could type 1.5 at first but the blood work came back and they said i was type 1.

i understand what type 1 is and what type 2 is and type 1.5 is mature onset in the young or MODY right? but what actually makes and type 1.5 and not 2 or 1 other then age? is it nearly the same as type 2 but just in someone aged ?? below, and if you reach over age ?? does it become type 2.

I know you can't change types, i'm just a little confused.

sorry may seem a silly question, i was curious. i don't want offend anyone.

thanks

Kt

Harold
11-23-2007, 04:01 PM
Not silly! Type 1 and 1.5 are essentially the same. The age of onset and the speed of onset are different. The cause appears to be the same. MODY is different in the cause is a specific genetic variation, and the action is a bit different than type 1 or 1.5. MODY resembles type 2 insulin resistance, but has a different specific genetic make up. Type 2 pure and simple is insulin resistance, and can cause beta cell burnout.

Typically;
Type 1 & 1.5 are the result of the autoimmune system destroying the beta cells, and 1.5 can happen anytime after reaching adulthood.

Type 2 insulin resistance, which can lead to destruction of beta cells from overuse.

MODY has specific genetic makers and resembles insulin resistance.

While one type will not change into another type. You can have one type and develop another type and have both types.

Type1 ans 1.5 seem to be age specific. In todays world the others are showing up at about any age.

miss_ok_ish
11-23-2007, 04:39 PM
don't you think that the body is quite amzing, so even though its not working to its best it has decided to act in a certain and is the same but not thesame, eg types hahah woah thats deep!

so another silly question, how do they know 100% that i am type 1 at 28 and not type 1.5 because of age? is that because the bloods show my beta cells are being destroyed by my ammune system and thats type 1? wow brain overload haha

sorry i know i have been told this in my diabetes clinics, but sometimes it goes in one ear and out the other! :)

JediSkipdogg
11-23-2007, 06:04 PM
There are quite a few tests that when all combined can pretty much tell your exact type, although they all have flaws since Diabetes is more complex than most think. The tests are as follows....

C-Peptice - This test measures the amount of C-Peptide in the blood. C-Peptide is produced at a ratio of 1:1 with insulin. The main problem is insulin is processed and removed by the liver in 5 minutes while C-Peptide is processed and removed by the kidneys in 30 minutes. Therefore there will generally be about a 5 times higher level of C-Peptide in the body than insulin, which is also why it's best to be done when insulin production is at it's lowest, fasting. This test mainly helps to determine type 2 or not, but can let a type 1 know their insulin production level if any.

GAD Antibody - This test tests specifically for the antibodies that cause type 1. If antibodies are present it means there is a higher chance of developing type 1 diabetes.

Glucose Tolerance Test - For this test numerous blood samples are drawn after fasting and then before/during a high carb fast acting sugar drink. A profile curve of your blood sugars are then drawn to seen how fast you return back to the fasting level. The longer it takes, the greater the chance of diabetes.

A1C - This is the #1 most commonly used test, although, it has many cons. The test shows an average of a person's blood glucose levels over 3 months. The average maximum life span of a blood cell is 3 months. Most, about 50% don't live past one month, but the rest live to 2-3 months old. As they are created, glucose sticks to the hemoglobin with your current BG reading. The problem is, people with different blood disorders may have innacurate A1Cs depending on how well their glucose bonds to the hemoglobin.



Those above tests are the most common ones used to diagnose diabetes. Upon initial diagnose some tests may be skipped or they may be changing rapidly. One major thing to remember is that if a person is retested, they should be retested in the same lab. This is due to some of the tests don't have standards for their meanings and they are created by the labs. The C-Peptide is the best example. There are no official standards to what the numbers mean, and truely the only way to figure out if the diabetes is progressing is to have tests done over time and compare the results.

I hope I helped some and didn't confuse you more.

Cyborg
11-23-2007, 06:11 PM
The GAD Antibody test is probably the most telling when it comes to differentiating between type 1 and type 2.

miss_ok_ish
11-23-2007, 07:13 PM
wow!

i'm based in englad so it early in the morning or really late at night and that was educational, i think i'll have another read tomz morning see if it siks in better, thanks jedi and cyborg x

lilituc
11-23-2007, 11:49 PM
so another silly question, how do they know 100% that i am type 1 at 28 and not type 1.5 because of age? is that because the bloods show my beta cells are being destroyed by my ammune system and thats type 1?

Well, the problem is that "Type 1.5" is used by different people to refer to different things. It's hard to know what your doctor was referring to when they said that. On here we use "Type 1.5" to refer to LADA, which is slow onset Type 1. The media sometimes uses "Type 1.5" to refer to double diabetes. Other people use it to refer to MODY. So you see that people may not be talking about the same things.

Type 1 can happen at any age. LADA is slow onset Type 1 found in adults (over 25-30). The main difference is speed of onset. People with regular Type 1 stop making insulin within months usually. People with LADA can have declining insulin production for years before they stop making insulin altogether. Hope this helps.