Just how long Novorapid last?

[ant hill]

Hey folks!!, How long Novorapid lasts in you?
For me I have had lows 5 - 6 hours since my shot. Can it be that I have been a diabetic for so long has a affect on how long insulin lasts in my body?

[xMenace]

Good question Peter. I've gone hypo 8 hours after my last stacked bolus before. I know the body breaks it down, but I don't know what the process is. A pharmacist explained it to me recently, but that brain cell must have died too :(

[ant hill]

Good question Peter. I've gone hypo 8 hours after my last stacked bolus before.

Thanks John, So I am not the only one with this lasting bolus.
According to Novo Nordisk they say 5 - 6 hours. Yeah right. :(
Just today I have bolused for lunch and buy 4PM I was in dreamland. :confused: and also have bolused hard too so it was my falt but this insulin can hang around for quite some time. Or is my basel can be looked at?

[Stuboy]

NovoRapid lasts for around 4 to 5 hours, if you're going low after that... perhaps you might need to evaluate your basal doses?

Just a thought :)

FYI...

NovoRapid Action Profile Information (http://www.novonordisk.com/diabetes/hcp/pharmaceuticals/novorapid/actionprofile.asp)

[JJM335]

According to Novo Nordisk they say 5 - 6 hours. Yeah right. :(
Just today I have bolused for lunch and buy 4PM I was in dreamland. :confused: and also have bolused hard too so it was my falt but this insulin can hang around for quite some time. Or is my basel can be looked at?

Peter:

I used to get a kick from the Novorapid tail at 5 h. If you want a quicker rapid-acting analog, you might want to try Apidra - with me, it's pretty much done its stuff by 3-3.5 h.

You could also be experiencing a basal effect. I tend to drop late afternoon, even though I have my Lantus dose as low as I can get it. I suspect that my basal requirements are lowest between about 4pm and 8 pm. Maybe you are the same.

Joel

[ant hill]

Apidra Huh, MMmm... I have gotten used to the Novoslow and the Novo insulin delivery.
Do Apidra have a good delivery system for thier insulins? What's the onset like...Fast!!!

[JJM335]

Peter:

Sonofi-Aventis insulins (Apidra and Lantus) are available (in the UK at least) in SoloStar disposable pens. These are perfectly adequate pens (as good if not better than the Novo flexpen). Although they don't have the solid feel (Mercedes-like quality) of the Novopen 3 or Novopen Jr, I have found them perfectly reliable. The only disadvantage is that the SoloStar doesn't do half-unit steps. Also, I am aware that disposable pens are not a very green solution. However, one advantage of disposables is that I can keep a spare at work in case I forget to bring my pen or lose it.

For me the Apidra is a much easier insulin to use. Carbs seem to go through my system almost instantaneously. I do find that the onset of Apidra is a bit quicker than Novorapid. However the biggest boon is that because it gets out of my system so quickly (50% gone in about 90 mins, 90% gone in about 3 h), corrections are much easier, and I don't have to worry so much about the "tail". I used to have constant hypos with Novorapid, which I have largely eliminated with Apidra. About the only downside is that for really big, slow digesting meals, e.g. pasta, I have to take 2 shots.

Of course it's a personal choice - however despite the nice Novopens, you couldn't pay me to go back to Novorapid.

Joel

[ant hill]

A very good post there Joel. Gee I have become a greenie of the diabetic world. :eek: Anyway If I where to be asked to try Apidra, I would look at the Solastar Pens and able to have a pen at work or elsewhere since the Basel insulins I generally take at home.
On the other subject that relates to activity and the insulin behavior I found that if you had gone for a walk and about to have lunch then your recent activity would make the Novorapid more active and prompt also the trouble with Dawn Phenomenon where your body is slowed than active. Anyway that's just my version on that.
With the Super Bolus like the Pasta, Pizza and the like I find that Novorapid (Or the Novoslow) I have come to understand on how this insulin reacts to my body. :)

[UpNorth]

I usually won't go low from Novorapid after 3.5-4h after having the injection... If i go low after that amount of time, it's usually due to physical activity...