View Full Version : difference between "A1c" and "glycated hemoglobin"?
While going through my time-of-DX hospital records, I noticed "glycated hemoglobin" of 19.0%. The reference range was <I forget the low end> to 7.8%, so it's apparently different than A1c... but I was even more over-the-top on that value.
Web searches tell me "glycated hemoglobin = A1c"... but the paperwork does not corroborate.
This perplexes me. Any thoughts?
xMenace
04-12-2008, 09:55 AM
It's your A1C.
Glycosylated hemoglobin - Wikipedia, the free encyclopedia (http://en.wikipedia.org/wiki/HbA1c)
It's your A1C.
Glycosylated hemoglobin - Wikipedia, the free encyclopedia (http://en.wikipedia.org/wiki/HbA1c)
Ehhh... I did the Google/Wikipedia thing already, looong before posting, and would tend to believe that... except one test showing 12.9% and another test showing 19.0%? That seems to be a bit of a divergence, even accounting for different methods...
xMenace
04-12-2008, 10:13 AM
Ehhh... I did the Google/Wikipedia thing already, looong before posting, and would tend to believe that... except one test showing 12.9% and another test showing 19.0%? That seems to be a bit of a divergence, even accounting for different methods...
I hope you don't put 100% faith in any lab test. I sure don't. lab test errors - Google Search (http://www.google.com/search?q=lab+test+errors&rls=com.microsoft:*&ie=UTF-8&oe=UTF-8&startIndex=&startPage=1)
I hope you don't put 100% faith in any lab test. I sure don't. lab test errors - Google Search (http://www.google.com/search?q=lab+test+errors&rls=com.microsoft:*&ie=UTF-8&oe=UTF-8&startIndex=&startPage=1)
Nope.
But both tests were performed at the hospital, within 24 hours of one another. And 12.9 and 19.0 are very different numbers. And, again, the reference ranges differed significantly...
...so I wondered if anyone else had any clues. I thought that I might be overlooking something simple and obvious.
Lloyd
04-12-2008, 03:08 PM
There ARE 2 sets of numbers. One is a percentage, the other a raw number.
The percentage is what gets used.
BlueSky
04-12-2008, 03:31 PM
The only other test I know of is the fructosamine test, but I would have expected it to be referred to as a "glycated protein" test.
There ARE 2 sets of numbers. One is a percentage, the other a raw number.
I thought both numbers were expressed as percentages. (Where did I put that packet?)
The only other test I know of is the fructosamine test, but I would have expected it to be referred to as a "glycated protein" test.
I'm certain that it said "hemoglobin".
I'll dig out the packet, reread to see if I'm in error about percentage/"hemoglobin", and take it from there. Thanks for the leads, guys! :)
I wonder if both numbers were indeed A1c tests, performed via different methods.
I should mention that, during the two months prior to DX, I'd been taking large quantities of vitamin C -- 55-80 g/day, with 65 g/day on average. Perhaps the high ascorbic acid consumption affected different tests differently.
Vitamin C, glycation, glycohemoglobin and aging (http://www.groupsrv.com/science/about14670.html)
Or, maybe it was what Lloyd said. Where did I put that packet?
jacobsam622
04-14-2008, 07:43 PM
There are several types of hemoglobin in a red blood cell. The glycosylated Hemoglobin measures how much sugar is stuck to all of The different kinds of hemoglobin in a red blood cell while the hemoglobin A1c measures how much sugar is stuck to a particular kind of hemoglobin - hemoglobin A1. The normal range for the A1C is about 2% lower then the total glycosylated Hemoglobin Levels.
There are several types of hemoglobin in a red blood cell. The glycosylated Hemoglobin measures how much sugar is stuck to all of The different kinds of hemoglobin in a red blood cell while the hemoglobin A1c measures how much sugar is stuck to a particular kind of hemoglobin - hemoglobin A1. The normal range for the A1C is about 2% lower then the total glycosylated Hemoglobin Levels.
This meshes well, considering that the top end of the "glycated hemoglobin" range was 7.8% -- which is indeed about two percentage points above the top end of the A1c range.
Thanks. :)
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