Type 1 daily insulin units/Kg

[BlueSky]

There have been some threads about insulin requirements and it would be interesting to graph this information. It would also help if weight is removed as a variable. So divide your total daily dose by your weight in Kilograms (Pounds divided by 2.2) to work out your number.

I am interested in seeing what the spread for Type 1 members is. Some of the variation will; be caused by things like level of carbohydrate consumption and whether MDI or pumping is used. But it will interesting to see what the distribution looks like .... ;)

[Scratch]

About .82

68 kg
approx avg of 56u per day the last 14 days

[Jan B]

.36 units per kg


(TDD = 20/ 56kg)

Average of about 40 carbs per day

[xMenace]

I put the .76 - 1.00 range, but I'm very close to the bottom number. Many days I do get under, but mostly I'm around .80

[RobiJo]

I put the .76 - 1.00 range, but I'm very close to the bottom number. Many days I do get under, but mostly I'm around .80

About the same. Some days is lower, others higher. Calc I did came out to .78

[grace girl]

63.6

.48 per kg

I average 30 units a day. Weight of 63 kg.

[Coppernob]

.36 units per kg


(TDD = 20/ 56kg)

Average of about 40 carbs per day

Jan, my insulin:kg ratio pretty much matches yours (20/55) - however I have more carbs than you do per day - 90 - 110 g per day. My basal must be lower as that is the only way this can occur - how do you manage to eat so few carbs and am I eating too many?

[Jan B]

Anne,

Let me know if this makes sense. My current basals are:

12a - .6
5a - .65
6:30a - .7
9a - .65
2p - .6

I take 1 unit for 16 cho & correction is 1 unit to lower 54

I went from extreme low fat to low carb (got bit by Bernstein!). Went from oatmeal for breakfast to omelets. I don't eat bread or any starchy vegetables anymore. I eat lots of spinach salads, flax muffins, and nuts. About the only carbs I eat are in peanut butter, sf jelly, green vegetables and fruit. I used to never eat meat . . . now I eat lots of turkey and fish.

If anyone thinks I'm crazy, it's fine to let me know. I can go a little overboard sometimes!!

[Dimes]

On an average day, 25U/95kg=0.26

I'm still making some insulin according to the doc..

[Coppernob]

Anne,

Let me know if this makes sense. My current basals are:

12a - .6
5a - .65
6:30a - .7
9a - .65
2p - .6

I take 1 unit for 16 cho & correction is 1 unit to lower 54

I went from extreme low fat to low carb (got bit by Bernstein!). Went from oatmeal for breakfast to omelets. I don't eat bread or any starchy vegetables anymore. I eat lots of spinach salads, flax muffins, and nuts. About the only carbs I eat are in peanut butter, sf jelly, green vegetables and fruit. I used to never eat meat . . . now I eat lots of turkey and fish.

OK yes that does make sense - at the moment my basals are:
12a.m. - .35
5 a.m. - .4
7 a.m. - .45
10 a.m. - .4
12 p.m. - .35
7 p.m. - .4
8 p.m. - .5

1 unit for 10g CHO; correction: 1 unit to 60
My eating habits have been becoming healthier with age :) and I too eat turkey and fish, as well as chicken for the most part. I am a big fan of salad and nuts. I guess my need for a bit of toast (1/2 a slice) in the morning, some yogurt at lunch and then my baked yam at night are where I overtake you carb wise. Those items alone account for ~60 g CHO - the difference between us I believe.

Thanks for the info, Jan - it is good to compare notes.

[notme]

.59 for me. :)

[shiftzor]

TDD/weight = 18/64 and eat around 200 carbs a day with some pancreas activity.

[sofaraway]

0.26 for me, TDD (average) 15 weight 56kg

[shabbie]

63.6

.48 per kg

I average 30 units a day. Weight of 63 kg.

mine is the same as yours holly!:cool:

[HelenM]

mine is the same as yours holly!:cool:
Is it something about 1.5. I weigh 63kg TDD 27 so very similar
(.43 per kg)

[Gordonm]

.55 or so.
Weight is 66kg
I am pumping about 36 units a day on average.
I consume about 175 to 200 carbs/day

[REDLAN]

I'm on .56u per Kg

that's with a daily carb intake around the 250g mark.

[Geoff]

31.5 units/80kg=.39 on av
eating 150grms carb/day avg

[Eddy]

84 kg (maybe a little less now)
300 +/- 20% grams of CHO per day (1:15 I:C ratio)
33 U basal

Typically low-50s U/day leaves me around 0.65 U/kg TDD.

[Eddy]

I am interested in seeing what the spread for Type 1 members is.


I'd like to see TDD/mass correlated with c-peptide levels and I:C ratios.

[solox316]

200 pounds = 91kg. Latest 31 day avg. = 59 units.

59/91=0.65units/kg.

32 units is basal, leaving about 27 units for CHO/Correction...

[BlueSky]

That poll has been an interesting exercise. Finding a "normal" insulin sensitivity reference point was not easy. The best I could find is John Walsh's suggestion that weight in pounds divided by 4 approximates the insulin need for someone with normal insulin sensitivity.
For those with Type I diabetes, insulin sensitivity can be estimated by filling in the blanks below:

1. Your weight (lbs.) / 4 =_____ units
2. Your total daily insulin dose (all insulins) =_____ units

The answer from line 1, (weight divided by 4) gives your estimated need for insulin. If your actual insulin dose on line 2 is close to this number, and you have good control, you have a normal sensitivity to insulin.

If line 2 is less than line 1 (and your control is good), you have excellent insulin sensitivity.

If line 2 is much greater than line 1, your insulin sensitivity may be lower or you may be on too much insulin.
Insulin Sensitivity (http://www.diabetesnet.com/diabetes_treatments/insulin_sensitivity.php)

This equates to 0.55 units/Kg for a person weighing 150 lbs. As a group, we appear to have pretty normal insulin sensitivity, according to this definition of normal.

Thanks for your responses ;)

[kstreeter513]

About 73kg
250-350 CHO/day
31 units TDD based on 30 day average
So somewhere around .43 u/kg

[shiftzor]

1. Your weight (141 lbs.) / 4 = 35.25 units
2. Your total daily insulin dose (all insulins) = 18 units

Surely Insulin resistance/sensitivity isn’t the only factor, beta cell productivity comes into play as well. It’s an interesting formula I wonder if once my beta cells finally give up the ghost my TDD will go up to the expected 35units or close to.

[BlueSky]

This calculation only applies to people with no residual beta cell function. There are other noise factors too, like level of carbohydrate consumption, insulin delivery method, age, hormonal activity etc. This is why there is variation around the norm. When your beta cells finally pack up, yes, you can expect to see an increase in exogenous insulin requirements towards this benchmark. But if you stay in shape and get lots of exercise, you should continue to be relatively insulin sensitive. My number works out to 0.47 units/Kg, but I have been T1 for 30 years and my beta cells are completely dead .... :(

[Funnygrl]

0.31 for me.

blah blah blah

[dbc]

TDD: 18u, 73Kg, 0.25/Kg
Lowish carb eating plan
My beta cells still do a bit. . . .

[Olidus]

So for me it looks like my 170lbs = 77kg
On Average 18 Units a day.
SO
I am at less then .25
More of a 0.23 if I did that right.

My Beta Cells are still doing some work for me.

[Scratch]

That poll has been an interesting exercise. Finding a "normal" insulin sensitivity reference point was not easy. The best I could find is John Walsh's suggestion that weight in pounds divided by 4 approximates the insulin need for someone with normal insulin sensitivity.


This equates to 0.55 units/Kg for a person weighing 150 lbs. As a group, we appear to have pretty normal insulin sensitivity, according to this definition of normal.

Thanks for your responses ;)
This is interesting.

I found the following reference in a book partially captured by Google Books --

Type 1 Diabetes in Children ... - Google Book Search (http://books.google.com/books?id=2lyIu4_5r4IC&pg=PA195&lpg=PA195&dq=puberty+increased+insulin+need+type+1+diabetics&source=web&ots=k1wJf2K6MG&sig=9VllyXAuLtW3I_hDUZHxrKHQCsQ&hl=en)

If I read that page correctly, it looks like that book says that for adults without diabetes, normal native I guess insulin production is on the level of .5 u/kg per day. But for adult diabetics, the sensitivity factor is more like .7 - .8 u/kg per day.

[BlueSky]

.... Type 1 Diabetes in Children ... - Google Book Search (http://books.google.com/books?id=2lyIu4_5r4IC&pg=PA195&lpg=PA195&dq=puberty+increased+insulin+need+type+1+diabetics&source=web&ots=k1wJf2K6MG&sig=9VllyXAuLtW3I_hDUZHxrKHQCsQ&hl=en)

If I read that page correctly, it looks like that book says that for adults without diabetes, normal native I guess insulin production is on the level of .5 u/kg per day. But for adult diabetics, the sensitivity factor is more like .7 - .8 u/kg per day.
That looks like a very a useful book. But I wonder why they distinguish between the insulin needs of normal adults and adults with type 1 diabetes. I can see no logical reason for an adult T1 to be more insulin resistant than a normal adult. :confused:

[Gary_W]

Now that I'm pumping, I am coming in at an average of 24.9u a day. I weigh just over 90kg. So that means I'm 0.27 and just miss out on the lowest category and sneak into the next group.

I tend to eat 220-250g of carbs per day from a wide variety of sources. Nothing is sacred :)