Allergic Reaction to Lantus

[carla1988]

[/FONT]

My mother has had Type 1 Diabetes for over 28 years. She was put on Lantus just under two weeks ago and is now suffering from general swelling and has a rash on her legs. She complains of a 'stretching' feeling all over her body. Her blood sugar level is otherwise under control. Could this be an allergic reaction?

She will be seeing her specialist tomorrow... I chose to ask for my own peace of mind.

Thanks...

[jtausch]

could be you can go webmd.com and look it up and see what the allergic reactions it list for lantus it would not hurt

[Jonathan_R]

SIDE EFFECTS

The adverse events commonly associated with LANTUS include the following:

Body as a whole: allergic reactions (see PRECAUTIONS).

Skin and appendages: injection site reaction, lipodystrophy, pruritus, rash (see PRECAUTIONS).

Other: hypoglycemia (see WARNINGS and PRECAUTIONS).

In clinical studies in adult patients, there was a higher incidence of treatment-emergent injection site pain in LANTUS-treated patients (2.7%) compared to NPH insulin-treated patients (0.7%).

The reports of pain at the injection site were usually mild and did not result in discontinuation of therapy. Other treatment-emergent injection site reactions occurred at similar incidences with both insulin glargine and NPH human insulin.

Retinopathy was evaluated in the clinical studies by means of retinal adverse events reported and fundus photography. The numbers of retinal adverse events reported for LANTUS and NPH treatment groups were similar for patients with type 1 and type 2 diabetes. Progression of retinopathy was investigated by fundus photography using a grading protocol derived from the

Early Treatment Diabetic Retinopathy Study (ETDRS). In one clinical study involving patients with type 2 diabetes, a difference in the number of subjects with ≥ 3-step progression in ETDRS scale over a 6-month period was noted by fundus photography (7.5% in LANTUS group versus 2.7% in NPH treated group). The overall relevance of this isolated finding cannot be determined due to the small number of patients involved, the short follow-up period, and the fact that this finding was not observed in other clinical studies.


Lantus (Insulin Glargine [rDNA origin] Injection) Drug Information: Uses, Side Effects, Drug Interactions and Warnings at RxList (http://www.rxlist.com/lantus-drug.htm)

[Jonathan_R]

What other meds is she on. I'm not seeing anything from lantus that would idicate a reaction like what you describe.

[Subby]

What is the her BG control doing? What was she using previously?

Those side effect sites are useful, but don't always seem to cover everything, no matter how much they claim to. If something really seems connected, I'd be taking cues from empirical observations and seeing if getting off it again helps. But the answers to the questions above might be relevant too...

[Aflfan]

My son had the same allergic reaction as many others have experienced. It began about a month after he began using it. Once we suspected the Lantus, we had him switched to Levimir. Problem solved. The hives stopped spreading and were completely gone after a month to a month and a half.
Hope this helps somebody.