Increased neuropathy when taking glumetza??

[dc1010]

Has anyone had increased neuropathy when taking glumetza??? I did not have any signs of neuropathy until I started taking glumetza a few months ago. The pain in my feet has become unbearable. I just am not sure if neuropathy comes on that quick. The doctor doesn't think it has to do with the glumetza and has recommended taking cymbalta, but I am not sure if I want to start another medication.

[Dis-N-Dat]

I'm so sorry that you are in such great pain. I can empathise, but haven't an answer for you. I do have 3 questions:

- Have you seen a podiatrist?
- Do you have ulcers or open lesions?
- Have you taken Neurontin?

- The Podiatrist can be a very good diagnostition for this.

- If you have open ulcers or lesions, they can become easily infected, even them may not "look" infected and this adds to your pain.

- Neurontin used to reduce nerve pain and has helped me alot.

I hope this is helpfull to you, The stress of the constant pain at thsat level can be not only draining, but damaging, especially to Diabetics.

As for coming on fast, in my case, it came on slowly in my legs and feet, but very fast in my arms and hands.

Please keep posting here, I'd like to now how you're doing.

[5539]

Has anyone had increased neuropathy when taking glumetza??? I did not have any signs of neuropathy until I started taking glumetza a few months ago. The pain in my feet has become unbearable. I just am not sure if neuropathy comes on that quick. The doctor doesn't think it has to do with the glumetza and has recommended taking cymbalta, but I am not sure if I want to start another medication.

I never had any signs of neuropathy either until I started taking glipizide/Janumet. My doctors did not think it was the cause of my problem either, and now I can hardly walk my left side is so weak and has pain like numbness. They put me on lyrica for the "neuropathy". I quit my diabetic meds. So far, two weeks, and a healthy diet, but no change. Help!

[sharpwaa]

God bless you, my neuropathy extends up to my chest with my abdomen and legs being the worst, sometimes the amytriptaline doesn't even dent it, although sometimes simple aspirin will be enou]gh to allow me to sleep. I recently went on to glyclazide before meals. Although my bloods have come down, funny things have happened since then, starting with a simple blister where my foot rubbed on new shoes, my foot now suffers from recurring ulcers with associated increased neuropathy pains and infection.Now then, is the increased pain because of the damage, or is it because I'm forced to be less active at these times? I suspect a bit of both is the answer.

[Robin1]

To my knowledge which is limited mainly to my experience I don't think you should have such a quick progression of painful neuropathy.

[REDLAN]

About 10-30% of metformin users can experience decreased absorption of vitamin B12.

Vit B12 deficiency as well as causing anemia can also cause neuritis (swelling of the nerves) the symptoms of which would be similar to neuropathy.

interesting article here

Metformin and Risk For Vitamin B12 Deficiency :: Diabetes Self-Management (http://www.diabetesselfmanagement.com/Blog/Amy-Campbell/metformin_and_risk_for_vitamin_b12_deficiency/)

and general article about vit b12 deficiency

Anaemia due to vitamin B12 deficiency (pernicious anaemia) (http://www.netdoctor.co.uk/diseases/facts/anaemiab12.htm)

note I haven't checked original sources to verify that this information is correct.

However it may be worth talking to your doctor about screening for Vit B12 deficiency.

Whilst searching I noted a paper whose title suggests that metformin induced vit12 deficiency can be improved by calcium supplementation. <haven't checked original source - might be nonsense>