I have thrown my Endo for a loop!

[lilmoe76]

Hi all- I am new and have only posted a few times but wanted to give you an update.
I have been reading your posts and know this is quite the educated group so wanted to run this by you. my Endo had waited to give me a "type" until labs came back-
Labs from 2 wks ago:
fbs-117
c-peptide-high normal
A1c-6.1 (I had done some major diet change since I found out about the D)
GAD-10

He said I am a Type 1 more than likely but is surprised I am managing as well as I am. He is calling the U of MN to see if they are doing any new research studies-I guess I am going to be a lab rat!

Whatever this all means,I am just to watch my blood and diet and go with the flow I guess...........

[plattb1]

Good news! Keep us posted!

[PrettynPurple]

really type one, did he give you insulin when he first diagnosed you??

because type 1's can't manage on diet alone (pancreas makes no insulin at all), not an expert but thats a pretty low FBS for a newly type 1 diagnosed. Or is that FBS after you made changes and was put on insulin? How long were you having sypmtoms before being seen by the endo???

[lilmoe76]

I was diagnosed a little over a month ago by my pcp, made changes immediately to my diet-that fbs is after changes.

I know, I am confused too! He said all his new Type 1's usually come to him from the hospital and on insulin already. He is just as confused! He did not have an explanation for my lab results at all!

No, I am not on any insulin or meds at this point....

hmmmm.....

[e||ement]

because type 1's can't manage on diet alone (pancreas makes no insulin at all)

just to clarify...the first part of this is correct...type 1s can't manage on diet alone.

the second part...pancreas makes no insulin at all...is not always the case.

those recently diagnosed T1 can be honeymooning and still producing a low level of insulin...but still require exogenous insulin.

it seems to me you would be type 2 with a high c-peptide level. or maybe 1.5? (i admit i don't know much about diagnoses of 1.5)

[foxl]

Okay-- first, welcome to the club -- we are called Type 1.5's or LADAs, and really we are different from Type 1's in more than the rate of onset of our Diabetes --- many (not all) of us also have insulin resistance, a characteristic of Type 2 D.

We also have a different antibody profile than "classic" type 1's -- we have more GAD antibodies, and less ICA and IA2antibodies, and there are other things ... interestingly according a recent review article, there are THREE TIMES as many of us as the classic Type ones.

If you look in PubMed.gov under LADA, there are quite a few recent reviews and I recommend you take them to your Endo -- although it does not, at this time, change the available therapeutic strategies.

You can control this by oral meds for a period of months to years, before going to insulin therapy, too. Everyone is different.

Hope this helps!

[shiftzor]

Okay-- first, welcome to the club -- we are called Type 1.5's or LADAs, and really we are different from Type 1's in more than the rate of onset of our Diabetes --- many (not all) of us also have insulin resistance, a characteristic of Type 2 D.

We also have a different antibody profile than "classic" type 1's -- we have more GAD antibodies, and less ICA and IA2antibodies, and there are other things ... interestingly according a recent review article, there are THREE TIMES as many of us as the classic Type ones.

If you look in PubMed.gov under LADA, there are quite a few recent reviews and I recommend you take them to your Endo -- although it does not, at this time, change the available therapeutic strategies.

You can control this by oral meds for a period of months to years, before going to insulin therapy, too. Everyone is different.

Hope this helps!

I agree and was the first thing I thought when starting to read this thread. Type 1.5 is most likely but without a Dr to diagnose it we cannot say for certain. I cannot believe the Dr hasn't even considered it?

[foxl]

I agree and was the first thing I thought when starting to read this thread. Type 1.5 is most likely but without a Dr to diagnose it we cannot say for certain. I cannot believe the Dr hasn't even considered it?

Considered it ... well, MY endo does not believe in it! So ... all stances, or lack thereof, are possible, apparently.

[telizas]

Wild!

If your doc hears of any studies, pass on the info. I live quite close to the U of M - that would be kind of cool!

[lilmoe76]

My Endo did mention Late Onset-LADA Type 1. From what I have read, this is also T1.5 (right?)
He is a wonderful Endo and I would put my life in his hands (well, I guess I already have huh?) He covered all the bases without me even asking!
I am curious about this honeymoon period I have heard about (my doc mentioned it too) Any good articles out there on it??

[Funnygrl]

The high c-peptide is interesting. Wouldn't be surprised if you have a bit of type 1.5 and type 2 going on (double diabetes). The fact that your c-peptide was high normal and your fasting glucose was still elevated suggests a degree of insulin resistance.

[lilmoe76]

Wild!

If your doc hears of any studies, pass on the info. I live quite close to the U of M - that would be kind of cool!

I sure will!

The high c-peptide is interesting. Wouldn't be surprised if you have a bit of type 1.5 and type 2 going on (double diabetes). The fact that your c-peptide was high normal and your fasting glucose was still elevated suggests a degree of insulin resistance.

Great, double diabetes, that is all a person needs!!:banghead:

[warrenav]

My Endo did mention Late Onset-LADA Type 1. From what I have read, this is also T1.5 (right?)
He is a wonderful Endo and I would put my life in his hands (well, I guess I already have huh?) He covered all the bases without me even asking!
I am curious about this honeymoon period I have heard about (my doc mentioned it too) Any good articles out there on it??

Not an article, but there are examples. I'm diagnosed as LADA, with D for 11 years and only using metformin, diet and exercise. However, my c-peptide was on the low side (just below normal range) and GAD was only a little into the high(positive) range. When you get into LADA (1.5), things become very individual and gray, not black and white. A high-normal c-peptide would argue for pancreas capability. However, c-peptide would normally be somewhat elevated with the elevated BG reading. Even I had a "normal range" c-peptide reading on a random test (since my BG at the time was somewhat elevated).

Warren.

[foxl]

The high c-peptide is interesting. Wouldn't be surprised if you have a bit of type 1.5 and type 2 going on (double diabetes). The fact that your c-peptide was high normal and your fasting glucose was still elevated suggests a degree of insulin resistance.

Actually for those who draw a line between LADA and 1.5, 1.5 includes includes insulin reistance; LADA may or may not.

[xMenace]

Be careful they don't lead you down a gopher hole! :eek:

[foxl]

Be careful they don't lead you down a gopher hole! :eek:

MMMMMhm! Gopher!