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GretchO
11-02-2009, 11:15 AM
Have been reading a lot of threads that use the term "liver dump" to account for most any rise in blood sugar, save the immediate effect of a meal. For example, not eating for a few hours causes a blood sugar rise of 20-30 points and is attributed to a "liver dump". Or 3 hours after eating the blood sugar is rising again and it's attributed to a "liver dump"

When I have what I consider to be a liver dump, it's usually the result of going very low, not correcting in time, and ending up with a blood sugar well into the 200s. For example, i go low overnight (into the 40s) and wake up with a blood sugar of 240.

So, I guess what I'm asking for is a good scientific explanation of what a "liver dump" is. Is DP a type of liver dump or is it a different thing/mechanism? Is any seeminly non-food related BS excursion a liver dump? Is an excursion of 30 points a liver dump? Does it depend? Is diabetes type a factor?

I googled it but it's hard to wade through all the forum-related links that come up. I was coming here to see if any of you smarties had something definitive in the way of a definition or possibly insight into the mechanisms of liver dumpage. What exactly is it?

foxl
11-02-2009, 11:26 AM
(edited to remove blatant reasoning errors)

... a liver dump is MOSTLY I am guessing, glycogenolysis ... http://en.wikipedia.org/wiki/Gluconeogenesis which is triggered by glucagon. (I am educable!) ...

http://en.wikipedia.org/wiki/Glucagon

thanks for the opportunity to REVIEW this stuff!

http://ezinearticles.com/?Understanding-Liver-Dump-Or-Dawn-Phenomenon-in-Diabetes&id=2422851

GretchO
11-02-2009, 12:10 PM
The first two articles made me hyperventilate...i was soooooo bad at biochemistry in college and i was a nutritional sciences major (i blame the teacher though...there are only so many times you can draw the krebs cycle on the board and expect people to pay attention). and my husband has a PhD in biochemistry...

foxl
11-02-2009, 12:50 PM
The first two articles made me hyperventilate...i was soooooo bad at biochemistry in college and i was a nutritional sciences major (i blame the teacher though...there are only so many times you can draw the krebs cycle on the board and expect people to pay attention). and my husband has a PhD in biochemistry...

Do what I do ... I majored in biology, was a bench chemist in SEVERAL biomed labs, including nutrition and pharm ... WING IT!

Focus on words, not structures ... ACK! :eek: It actually makes some sense then!