More news on a cure

[BriOnH]

http://www.upi.com/ConsumerHealthDaily/view.php?StoryID=20060327-034519-2918r

here is a quote from the news article:
"The injections interrupted the T cell and beta cell interaction, allowing the beta cells in the pancreas to regenerate. This enabled the pancreas of the mice to begin producing insulin again. The injections proved capable of stopping this vicious cycle, and through this process curing type 1 diabetes in a mouse."

I find it hard to believe that our pancreases keep trying to create beta cells which in turn just get 'picked off' by our immune system, but hey, be great if it were true. Be interesting to see how the trials go.

[koblenz]

I find it hard to believe that our pancreases keep trying to create beta cells which in turn just get 'picked off' by our immune system, but hey, be great if it were true. Be interesting to see how the trials go.

I don't know... I bet my pancreas is just that stupid ... the rest of me is...

[seacomp]

Be interesting to see how the trials go.
There are two different experiments reported in the recent period that have shown the possiblity of reversing Type 1 in mice, both are going on to small scale clinical trials soon. This one with dendrite cells and the other with stem cells. Both have been reported in the Forum here.
It looks hopeful that some means of reversing Type 1 is feasible in the foreseeable future.
That would be wonderful!:love: :love: :love: I am glad for you guys!
From what I've read, I suspect that the reversal may only be possible in the early stages of the disease. What this means for particular people, I have no idea.

[Cyborg]

Heck, I'd volunteer for those trials...

[HelenM]

I find it hard to believe that our pancreases keep trying to create beta cells which in turn just get 'picked off' by our immune system, but hey, be great if it were true. Be interesting to see how the trials go.
I have read that anti GAD cells are found for some time (years) after diagnosis but less frequenly in people who have had type 1 for a long time which would suggest continuing attacks .
A year ago when I was first diagnosed I found a paper (which I'm trying very hard to relocate) which suggested just this for the development of 1.5 or LADA.
It suggested that a low level virus (possibly the one that causes hand, foot and mouth in children and apparently is very similar to a beta cell) overstimulated the antibodies which destroyed some of the beta cells which then partially (in number) regenerated. Further attacks of the same virus over time eventually causing more losses and tipping the person under the level necessary to produce sufficient insulin.

[BriOnH]

I don't know... I bet my pancreas is just that stupid ... the rest of me is...

I think the real cure, the one what will actually work, will require MORE COWBELL!

http://fourthandshawn.com/images/cowbell.jpg

Sorry, I couldn't resist, I love that sketch!! Love your sig K

[dws]

I have really been upset about the increase of diabetic mice! Now that they can reverse diabetes in mice I feel much better. think i'll sleep much better and longer now that that worry is taken care of. :)

I am wondering where we stand in the 'Cure" Are we AFTER the cats, dogs, sheep, cows, horses, goats etc.??????? :biggrin:

don

[BriOnH]

I have really been upset about the increase of diabetic mice! Now that they can reverse diabetes in mice I feel much better. think i'll sleep much better and longer now that that worry is taken care of. :)

I am wondering where we stand in the 'Cure" Are we AFTER the cats, dogs, sheep, cows, horses, goats etc.??????? :biggrin:

don
lol
I think we are last since we're the only ones who pay for diabetic supplies. (Almost) All kidding aside, the mouse model is neat, and promising, but is no where near as complex as the human model. Dr. Faustman has stated this before and the complexities that have to be over come to cure humans.