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Loss of Weight and Muscle Mass

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#1
deercotn

deercotn

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I'm a Type 2. I take metformin 500mg 3x daily (with each meal).

I've lost 20 lbs over the past 3-4 months. In another forum, some have suggested that the metformin could be causing some of the weigh loss. Anybody with a similar experience?

Regardless, since I've been diabetic, I've lost weight, gained some back, and lost again, etc. I've also lost muscle tone and mass. I don't consider myself really "overweight". I'm 6'2" and currently weigh 200 lbs. My heaviest ever was 235 and as recently as March I weighed 223.

I'd like to gained some weight back and gain muscle tone and mass. But obviously I assume I need to stay away from carbs? Also, I have slight to moderate reduced kidney function (GFR 58) so I'd be concerned about taking in too much added protein?

My exercise routine right now is a 2 mile walk/jog pretty much every day. I'm thinking about starting to lift weights maybe every other day. Will this help gain weight and muscle mass/tone? What supplements can a diabetic safely take that won't raise my blood sugar and be harmful to my kidneys?

I really appreciate any help and advise. Thanks.
Diagnosed 09/2003
BG at diag 324
A1c at diag 9.7
Lowest A1c 6.0 (08/09)
Most Recent A1c 6.4 (06/10)
Glyburide-Metformin 2.5-500mg 3x daily
Enalapril
Norvasc
Crestor
Fish Oil 1000 mg 2x daily
Levitra ....
:D
Brisk walk 30 min 5x weekly

[SIGPIC][/SIGPIC]

#2
dbaratta

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I'm a Type 2. I take metformin 500mg 3x daily (with each meal).

I've lost 20 lbs over the past 3-4 months. In another forum, some have suggested that the metformin could be causing some of the weigh loss. Anybody with a similar experience?

Regardless, since I've been diabetic, I've lost weight, gained some back, and lost again, etc. I've also lost muscle tone and mass. I don't consider myself really "overweight". I'm 6'2" and currently weigh 200 lbs. My heaviest ever was 235 and as recently as March I weighed 223.

I'd like to gained some weight back and gain muscle tone and mass. But obviously I assume I need to stay away from carbs? Also, I have slight to moderate reduced kidney function (GFR 58) so I'd be concerned about taking in too much added protein?

My exercise routine right now is a 2 mile walk/jog pretty much every day. I'm thinking about starting to lift weights maybe every other day. Will this help gain weight and muscle mass/tone? What supplements can a diabetic safely take that won't raise my blood sugar and be harmful to my kidneys?

I really appreciate any help and advise. Thanks.

How Long Does It Take For Metformin To Work?
A1C JULY 2010 5.9%
A1C March 2010 6.2%
Lantus 16 units split dose
Novolog as needed


:aetsch:

#3
deercotn

deercotn

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Bump.

Just trying to get some response to my original post.

I could use some advise.

Anyone?
Diagnosed 09/2003
BG at diag 324
A1c at diag 9.7
Lowest A1c 6.0 (08/09)
Most Recent A1c 6.4 (06/10)
Glyburide-Metformin 2.5-500mg 3x daily
Enalapril
Norvasc
Crestor
Fish Oil 1000 mg 2x daily
Levitra ....
:D
Brisk walk 30 min 5x weekly

[SIGPIC][/SIGPIC]

#4
fgummett

fgummett

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I'm sure I'll be corrected, but I don't see losing substantial amounts of lean muscle unless you are not eating enough protein. This can be a problem with the calorie-restricted diet -- everything is reduced, so while you may lose "weight" it may not all be from "excess fat mass".

Many people voice concerns about eating higher levels of protein with reduced kidney function but I assume that you under a specialists supervision for the reduced renal function... and losing muscle mass is also serious, quite apart from all the other reasons our bodies need protein -- making insulin for example.

If it were me, I would carefully increase my protein intake -- keep a log -- while asking for additional renal follow up with urine and blood tests.

You may be interested to read this related study The Impact of Protein Intake on Renal Function Decline in Women with Normal Renal Function or Mild Renal Insufficiency
...with these conclusions from the publications editors

Context
Although dietary protein restriction appears to slow the decline in renal function among patients with moderate renal insufficiency, its effect on normal and mildly decreased renal function is unknown.
Contribution
Among women from the Nurses’ Health Study with normal renal function, protein intake was not associated with decline in glomerular filtration rate (GFR). In women with mild renal insufficiency, high protein intake, particularly of nondairy animal origin, was associated with more rapid than expected decline in GFR.
Implications
High protein intake is associated with declining GFR among women with mild renal insufficiency. A causal connection has not been demonstrated. Additional studies are needed to show that reducing protein intake protects the kidney.
–The Editors


Dr Richard Bernstein claims much improvement to his own reduced renal function once he switched to his now famous dietary paradigm.

#5
MCS

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DeerCnt, have you looked into the Amino Acids I suggested. I thought I saw where the L-Arginine was actually benefical for people with Kidney function problems. Are you monitoring your protien out put thru your kidneys?




I'm a Type 2. I take metformin 500mg 3x daily (with each meal).

I've lost 20 lbs over the past 3-4 months. In another forum, some have suggested that the metformin could be causing some of the weigh loss. Anybody with a similar experience?

Regardless, since I've been diabetic, I've lost weight, gained some back, and lost again, etc. I've also lost muscle tone and mass. I don't consider myself really "overweight". I'm 6'2" and currently weigh 200 lbs. My heaviest ever was 235 and as recently as March I weighed 223.

I'd like to gained some weight back and gain muscle tone and mass. But obviously I assume I need to stay away from carbs? Also, I have slight to moderate reduced kidney function (GFR 58) so I'd be concerned about taking in too much added protein?

My exercise routine right now is a 2 mile walk/jog pretty much every day. I'm thinking about starting to lift weights maybe every other day. Will this help gain weight and muscle mass/tone? What supplements can a diabetic safely take that won't raise my blood sugar and be harmful to my kidneys?

I really appreciate any help and advise. Thanks.


---------------------------------
Asprin 2-6 325mg per day
Amino Acids, Vitamins Bx, C, D, E
Hi-Maize 260, Ground and Whole Flax Seed
COQ10, Magnesium, Zinc, Fish Oil, Lisinopril
A1C estimate of 10-12 at dxed 5.6, 4.8, 4.6
Everyone has something to offer, you just have to listen

#6
Dis-N-Dat

Dis-N-Dat

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Lifting should increase your muscle mass, but with the complication of your kidney function I'd be afraid to give you advice other than to speak to your doc and nutritionist.

The nutritionist (my first visit, I'm still new at this) reminded me:

-Muscles (especially your heart) use carbs first for energy.

-Your body is very efficient with protein,..ie a little goes a long way.

-When every you can, use the food not the supplement.

Hope this helps a little.

"There are two ways to live your life. One is as if nothing is a miracle, the other as if everything is".
...Albert Einstein...

[SIGPIC][/SIGPIC]


Georgia
T2 dx 07/18/09
Metformin 500mg bid
Neurontin 300mg bid
Cyclosprine 200mg bid
Lisinopril 20mg
Celexa 20mg
Warfarin 7.5mg

#7
MCS

MCS

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Do not want to advocate anything until you consult your doc, but here is an article on the benefits of L-Arginine for people with kidney function and congestive heart failure problems. Hopes this helps:

Life Enhancement:: Arginine Keeps Kidneys in the Pink
---------------------------------
Asprin 2-6 325mg per day
Amino Acids, Vitamins Bx, C, D, E
Hi-Maize 260, Ground and Whole Flax Seed
COQ10, Magnesium, Zinc, Fish Oil, Lisinopril
A1C estimate of 10-12 at dxed 5.6, 4.8, 4.6
Everyone has something to offer, you just have to listen




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