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Alternative to Januvia

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#1
ChristyJ

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I am currently taking 500mg TR Metformin. My BG is climbing and my doctor has prescribed Januvia. It is so expensive. Is anyone aware of another drug that helps your insulin become more effective? I also take 2 blood pressure meds and a statin.
Christy

Diagnosed Type II - 7/8/2005- A1c- 5.4
3/29/06- A1c- 5.8
3/14/07 -A1c- 6.0
6/17/08- A1c- 5.7
12/29/08 -A1c- 5.8
6/30/09- A1c- 6.5


Metformin 2-500mg TR
Crestor
Allopurinol
Atenol
Amitriptyline 100mg
Lisinopril
aspirin 325 mg

#2
ShottleBop

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You might consider talking to your doctor about using insulin itself.
Functionally, a Type 2 (missed the label by th-a-a-a-a-t much)
Dx prediabetic 02/08 (FBG 127 and 123), A1c 6.5
So far, controlled without meds.

#3
jerryn

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Januvia messed my thyroid up and caused termporary hypothyroidism. Just what a type 2 needs LOL.. so I am on gliburide now. And gliburide works well with me. I take gliburide, Metformin + Bayetta.

#4
foxl

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Januvia messed my thyroid up and caused termporary hypothyroidism. Just what a type 2 needs LOL.. so I am on gliburide now. And gliburide works well with me. I take gliburide, Metformin + Bayetta.


I was considering Januvia -- it messed with your THYROID, though???? ACK.

I did not know it was still expensive, either ... (leans back toward insulin).
Linda


[B]Jan A1c 6.3/B]
Jul 09 ... C-pep 1.3, GAD-65 > 30
Mar 10 C-pep 2.8 (20 g carb); GAD 3.2
dx 02/09 in DKA


Levemir 12U per day; novolog PRN TDD ca 16U
MetforminXR 1000 mg BID
Ramipril 5 mg
T4 112 mcg
Chia oil
Vitamin D3, 4000 IU
Eating 20 - 45 g carb per day ovo-lacto-vegetarian
Walking 30 min 6x week

#5
cherokee_psh

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I was considering Januvia -- it messed with your THYROID, though???? ACK.

I did not know it was still expensive, either ... (leans back toward insulin).


Full price there is not a generic version at this time. I have been taking it for over a year and it has not messed with my thyroid.

I don't think insulin would be cheaper then Januvia either. Using my insurance (last year, I've not checked this years numbers), I would pay $25 over what I pay for Januvia.

That being said, I have been told by both my endo and primary that Januvia alone has a limited life. At some point it will stop working for you. Then it will be replaced or combined with other medications.
Susan

:flybye:

A1C - 6.9
Meter - Freestyle Lite

Medication
125 mcg Synthroid
100 mg Januvia
Latanoprost Eye Drop
Simvastatin 10 mg
Lantus SoloSTAR 10 units

#6
sanflan

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About 2 weeks ago my doctor gave me samples of Actos. It, along with taking insulin, seems to be working well for me ( I am waking up with 98 blood sugars as opposed to 198) I don't know how expensive it is, but it seems to be the best I have taken so far.

I did take Metformin and Glucotrol. I don't mind Metformin as long as there is a bathroom handy and I just read that Glucotrol might not be as safe as once thought. But the Actos and Insulin seems to be the best for me.

#7
foxl

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Full price there is not a generic version at this time. I have been taking it for over a year and it has not messed with my thyroid.

I don't think insulin would be cheaper then Januvia either. Using my insurance (last year, I've not checked this years numbers), I would pay $25 over what I pay for Januvia.

That being said, I have been told by both my endo and primary that Januvia alone has a limited life. At some point it will stop working for you. Then it will be replaced or combined with other medications.


Susan, still, as a Type 1.5, I would rather pay more for insulin, avoid further deterioration of my thyroid, and hope it is helping preserve my beta cell mass, when Januvia probably would not. ;)
Linda


[B]Jan A1c 6.3/B]
Jul 09 ... C-pep 1.3, GAD-65 > 30
Mar 10 C-pep 2.8 (20 g carb); GAD 3.2
dx 02/09 in DKA


Levemir 12U per day; novolog PRN TDD ca 16U
MetforminXR 1000 mg BID
Ramipril 5 mg
T4 112 mcg
Chia oil
Vitamin D3, 4000 IU
Eating 20 - 45 g carb per day ovo-lacto-vegetarian
Walking 30 min 6x week

#8
ChristyJ

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About 2 weeks ago my doctor gave me samples of Actos. It, along with taking insulin, seems to be working well for me ( I am waking up with 98 blood sugars as opposed to 198) I don't know how expensive it is, but it seems to be the best I have taken so far.

I did take Metformin and Glucotrol. I don't mind Metformin as long as there is a bathroom handy and I just read that Glucotrol might not be as safe as once thought. But the Actos and Insulin seems to be the best for me.


Thanks for the info. I will discuss Actos with my physician. I have not gone on insulin yet. I tolerate Metformin fairly well but I can really identify with the "where is the bathroom syndrome."
Christy

Diagnosed Type II - 7/8/2005- A1c- 5.4
3/29/06- A1c- 5.8
3/14/07 -A1c- 6.0
6/17/08- A1c- 5.7
12/29/08 -A1c- 5.8
6/30/09- A1c- 6.5


Metformin 2-500mg TR
Crestor
Allopurinol
Atenol
Amitriptyline 100mg
Lisinopril
aspirin 325 mg

#9
ShottleBop

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Check out Blood Sugar 101 regarding Actos, as well. Actos and Avandia:

lower blood sugar by decreasing insulin resistance. They do this by causing the formation of new fat cells primarily on the arms, thighs, and butt. These new fat cells then take glucose out of the blood stream.

. . . the manufacturers' own prescribing information makes it clear that these drugs produce only a modest change in blood sugar and insulin levels, though possibly a bit more than Metformin.


Functionally, a Type 2 (missed the label by th-a-a-a-a-t much)
Dx prediabetic 02/08 (FBG 127 and 123), A1c 6.5
So far, controlled without meds.

#10
foxl

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Check out Blood Sugar 101 regarding Actos, as well. Actos and Avandia:


Add to those, Actos apparently causes bone loss ... to the point of "spontaneous fractures!" Which is why my Endo did not want me on it.

Lilly's Actos trial shows increased fracture risk in women | Adverse Event Reporting News | Find Articles at BNET
Linda


[B]Jan A1c 6.3/B]
Jul 09 ... C-pep 1.3, GAD-65 > 30
Mar 10 C-pep 2.8 (20 g carb); GAD 3.2
dx 02/09 in DKA


Levemir 12U per day; novolog PRN TDD ca 16U
MetforminXR 1000 mg BID
Ramipril 5 mg
T4 112 mcg
Chia oil
Vitamin D3, 4000 IU
Eating 20 - 45 g carb per day ovo-lacto-vegetarian
Walking 30 min 6x week

#11
sanflan

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I have put off using Actos for many years. But, no matter what I take including hugh amounts of insulin, metformin, with glucotrol, I could not get my BG down. This is the first time my morning BG is less than 190 in the last few years. I don't know which is worse having my bones break or losing my legs and eyesight. I guess it is a toss up on bad outcomes.

#12
ChristyJ

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Januvia messed my thyroid up and caused termporary hypothyroidism. Just what a type 2 needs LOL.. so I am on gliburide now. And gliburide works well with me. I take gliburide, Metformin + Bayetta.


I'll take a look at gliburide. Thanks.
Christy

Diagnosed Type II - 7/8/2005- A1c- 5.4
3/29/06- A1c- 5.8
3/14/07 -A1c- 6.0
6/17/08- A1c- 5.7
12/29/08 -A1c- 5.8
6/30/09- A1c- 6.5


Metformin 2-500mg TR
Crestor
Allopurinol
Atenol
Amitriptyline 100mg
Lisinopril
aspirin 325 mg

#13
sanflan

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I have just quit taking Glipizide, when I read a recent alert that it caused more heart attacks and sudden deaths.

Do any of the type 2's just take insulin alone and does it work for you?

#14
stinastina

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I am on Actos again trying to get back on track, but as soon as my numbers get better, I will get off it. My feet are swollen every night and I am gaining weight. Not to mention the night cramps.

Now Januvia I get results from. You can go to the Merck site and they have information on getting your medicine free if you qualify. Many pharmaceutical companies have similar programs.

Current meds:
2000 mg Metformin
25 mg HCTZ
50 mg Losartan

Current supplements:
Iron
Centrum Multivitamin
300mg Mega Red Krill Oil

Vitamin D

r-ALA

HbA1c

4/23 - 6.5  :proud:

4/14 - 6.8 
3/14 - 6.9 :D
2/14 - 7.4
1/14 - 8.1
12/13 - 7.9
4/5/10 - 6.7 :)
12/18/09 - 7.9
6/22/09 - 7.2
3/19/09 - 11.8 :eek:
2/5/09 - 10.4 (just starting meds)

I've lost 23 lbs since 1/15/14 !! :D


#15
djt1344

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Hi Guys,

Just been coughing badly lately and stopped Lisinopril and started something called Cozaar 2 days agao with Mucinex dm. Just got home from eating 3 pieces of KFC gril chicken with half a diet pepsi, feeling not well like dry mouth and food is stuck in the tummy, please help anyone.

Daniel

#16
jtausch

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I have just quit taking Glipizide, when I read a recent alert that it caused more heart attacks and sudden deaths.

Do any of the type 2's just take insulin alone and does it work for you?


I was on met for 6 months than went to insulin only when i saw an endo for the first time My last two A1c on insulin only was 5.5 and 5.6 so insuluin works for me.
Diagnosed: DEC-08-08: FBS 304 :A1c 12.2:mad:
Minimed Paradigm 723 Revel 12-04-2012
Bayer contour next easy link
NEWEST: A1c 6.0 FBS 97 02/12/13:)
Plavix 75 mg;Aspirin 325 mg;Coreg 2.5 mg
Lisinopril 5.0 mg;Lipitor 20 mg


:)




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