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Can Januvia Elevate TSH levels?

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    Junior Member

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I am Type 2 diabetic and have been on Metformin ER for a few years. My thyroid tests have always been normal. Three months ago I was put on Janumet (combination Januvia and Metformin). I just went for bloodwork and for the first time ever my TSH is elevated (5.04) and my T4 Free is low (.8). Does anyone know if the Januvia is responsible for these changes? It seems more than a coincidence. My next appointment with my endocrinologist is in 3 months and I will repeat these tests again.



    Senior Member

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I will be interested to hear if there is anything behind this ... someone else here recently posted Januvia messed up his thyroid!

I was considering trying it for postprandial peaks ... I think I am leaning once again toward insulin, when needed, though!

[B]Jan A1c 6.3/B]
Jul 09 ... C-pep 1.3, GAD-65 > 30
Mar 10 C-pep 2.8 (20 g carb); GAD 3.2
dx 02/09 in DKA

Levemir 12U per day; novolog PRN TDD ca 16U
MetforminXR 1000 mg BID
Ramipril 5 mg
T4 112 mcg
Chia oil
Vitamin D3, 4000 IU
Eating 20 - 45 g carb per day ovo-lacto-vegetarian
Walking 30 min 6x week