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Sulfa & Sulphonylureas Allergy

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#1
sheilarenee

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Does anyone know if you are allergic to Sulfa, does this mean you shouldn't take a sulphonylurea, like Glipizide? I am allergic to Bactrim, & took Glipizide in 2007. I got a rash 3x in 2 months, so I thought it was the Glipizide & stopped taking it, even though it was working good. Recent events have lead me to believe, that my rashes were not from Glipizide. Anyone know if you are allergic to sulfa, is it ok to take Glipizide?

Thanks for the help!
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Diagnosed 05/07- A1c 12.7
02/10- A1c 6.9 :)
11/10 A1c 8 :(
2/11 A1c 8.1 :confused:
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#2
mortis505

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From page 3 and 4

Diabetes: Type 2 - Medications

Side Effects and Complications. In general, sulfonylureas should not be used by women who are pregnant or nursing or by individuals who are allergic to sulfa drugs. Side effects may include:

Weight gain (some sulfonylureas, such as glimepiride, may produce less weight gain than others)
Water retention
Although sulfonylureas pose a lower risk for hypoglycemia than insulin does, the hypoglycemia produced by sulfonylureas may be prolonged and dangerous. The newer sulfonylureas, such as glimipiride, have much less risk of hypoglycemia than older sulfonylureas.
Some sulfonylureas may pose a slight risk for cardiac events.
Sulfonylureas interact with many other drugs, and patients should be sure to inform their doctor of any medications they are taking, including alternative or over-the-counter drugs.


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#3
adiantum

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I'm alergic to sulfur & unable to take such drugs as glipizide, metformin etc..not that I would take them anyway as insulin is the prefered way for me.
I also avoid preservatives . Ham & bacon will cause a rash for me.
Dx Dec 07 Type2
Control...nutrition & exercise

#4
sheilarenee

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Thanks-I told my doctor I was allergic to Sulfa before I was EVER given Glipizide. I wonder if doctors know anything sometimes!!??!!
[SIGPIC][/SIGPIC]
Hello from New Orleans :shakehand
Diagnosed 05/07- A1c 12.7
02/10- A1c 6.9 :)
11/10 A1c 8 :(
2/11 A1c 8.1 :confused:
Lantus
Metformin 500mg 2x a day -down from 1000mg :)
Fish Oil - 2x a day
Cinnamon & Chromium- 2x a day
VERY Low Carb since April 2011

#5
adiantum

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My alergy is also recorded at the pharmacy I mostly frequent, just in case the doctor slips up & prescribes something with sulfa.
Dx Dec 07 Type2
Control...nutrition & exercise

#6
diabeticguy18

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Im allergic to sulfa and stay away from ANYTHING that contains it,
I was to young to remember the symtoms but my mom has told me i break out in an insatiable rash and hives.

On the doctor thing I know what you mean :( . I went to my primary along while back and she FORGOT I was diabetic!!!!!!!

#7
wlh34

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Does anyone know if you are allergic to Sulfa, does this mean you shouldn't take a sulphonylurea, like Glipizide? I am allergic to Bactrim, & took Glipizide in 2007. I got a rash 3x in 2 months, so I thought it was the Glipizide & stopped taking it, even though it was working good. Recent events have lead me to believe, that my rashes were not from Glipizide. Anyone know if you are allergic to sulfa, is it ok to take Glipizide?

Thanks for the help!


I brought this issue to the attention of presenters of the diabetes advice/diet class I attended and was told to stay away from sulphonylureas.

I had very noticeable visual disturbances when taking sulfa for a wound caused by a fall from a tree when just a pup.

Probably close to 65 years ago. And I haven't got close to the stuff since. FWIW

Bill

..........Hb1AC... FBG...Chol....LDL...HDL....Trig :eek:
08/06 : 6.5% 174 195 XXX 41 188 DX Type 2
11/07 : 6.5% 112 243 155 37 270
10/08 : 6.8% 127 242 127 40 373
10/09 : 5.6% XXX 181 090 60 157
10/11 : 5.7% 117 188 100 49 194
10/12 : 5.8% 120 179 078 45 279
05/13 : 5.7% 117 177 095 52 150
Weight : 2006 high = 185; 2013 = 150 stable

#8
pradyot biswas

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The older sulfa drugs were known as sulphonamides. Those were mostly used as bacteriostatic agents. chemically, in those sulphonamides group three chemical entities remained which were responsible for allergies. Sulfur has many types of salt aand some of which chemically lacks those contents which are supposed to be responsible for allergy. Though sulfonylureas contains sulfur but it has no such chemical structures like sulphonamides and hence should not so any manifestation of sulfur allergy. In fact, my wife is regularly taking 2mg. of glimeperide for last 3-4 yrs. though she has a record of sulfur allergy. Will be grateful if anybody knows more about this topic and convey it.
Pradyot Biswas




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