For those of who who seem to fall through the cracks...
"If we start by asking a few questions, the need for a reclassification or enhanced definition of diabetes becomes more apparent.
- Is a patient with type 1 diabetes immune to developing type 2 diabetes in their lifetime, or can they possess features of both, such as dysmetabolic syndrome?
- Is it possible for the patient with type 2 diabetes to progress to insulinopenia, become ketosis prone, or even possess immune markers during the course of their disease?
- Are there type 1 diabetic patients who never test positive for antibodies, and are thus non-autoimmune yet insulin dependent?
...When a patient presents or progresses in their disease with characteristics beyond the current definition, A V+ for variance would be added to the T1 (Type 1) or T2 (Type 2) nomenclature.
...Then the modifier that the patient exhibits would be added to the variant. Such as Ab +/- for antibody status, K +/- for Ketosis prone, IR +/- for insulin resistance, P 1/2/3 for phenotypic features, and in the future G typing for Genetic Allele expression.