[lottadata]

At my endo appt last week the doc suggested I try Prandin. So I've been using it for the past week.

It's a bit strange how it's been working. I started out with 1/4 of the .5 mg pill and with 25 g for breakfast, I was going up to about 140 at 1 hour and then dropping to the 90s at 2 hours.
So that looked promising. No runaway hypos like with Amaryl and no overwhelming hunger, ditto.

So I upped the dose to 1/2 of the .5 mg pill to see what it would do and it covered 20-40 grams pretty well at both breakfast and lunch . I would usually use 2-3 units of insulin to cover that much carb.

But every time I use it for dinner, it's another story. I was spiking to the 170s at 1 hour and then ending up 120 a couple hours after dinner seemingly independent of how many grams of carbs I ate. With injected insulin I could stay under 140 and be down to the high 80s for the same meal. It's almost like my beta cells said, "Two meals is enough" and gave up.

I tried using a whole .5 mg pill today with a too carby lunch (long story. I won't do it again. <G>) and went up to 158 at 1 hour. I did a 40 minute uphill hike and ended up at, 95 at 2 hours. Not good. And not any different than what I was getting with 1/2 of the .5 mg pill.

So I'm concluding that Prandin will work for me, sort of. It isn't like insulin where I can match it to food intake. If I'm going to use it, I probably better keep the carbs to 30-ish.

Had I never used insulin, I'd probably be happy with the Prandin, because taking it sure beats the days when I had to eat under 12 grams per meal and even then go higher than I'm going with the Prandin. But a couple years of using insulin has got me a bit spoiled.

I'll keep fooling with this stuff, seeing if changing the timing makes any difference in how it works.The convenience is a plus--no carrying around insulin that can go bad on hot days--but the not so great blood sugars are not. Nor is the fact that I can't eat a normal meal with it and NOT get a wicked high spike, even if it comes down to something nonlethal later.