[Hikeandbike]

Okay, When I had the C-peptide done doc said I was still producing insulin. This was done when I first went to my Endo. My GP had already put me on insulin. Would this bias the C-peptide test?
Thanks
Rich

[JediSkipdogg]

No, when insulin that we inject is manufactured they actually remove the C-Peptide from insulin. This is done because in the creation of insulin they have to break it down to it's most basic form and pull the insulin out. It would then cost more money to add the C-Peptide in. That's on top of the fact that C-Peptide breaks down alot faster than insulin and therefore would make it expire much sooner.

Therefore injected insulin contains no C-Peptide.

[xMenace]

Originally Posted by JediSkipdogg

No, when insulin that we inject is manufactured they actually remove the C-Peptide from insulin. This is done because in the creation of insulin they have to break it down to it's most basic form and pull the insulin out. It would then cost more money to add the C-Peptide in. That's on top of the fact that C-Peptide breaks down alot faster than insulin and therefore would make it expire much sooner.

Therefore injected insulin contains no C-Peptide.

Even though there are claims that they would help us ward off complications.

YouTube - Love Diabetes: The blasphemy of C-peptide Removal

[JediSkipdogg]

Originally Posted by xMenace

Even though there are claims that they would help us ward off complications.

YouTube - Love Diabetes: The blasphemy of C-peptide Removal

I wasn't going to bring that part up but yup. I guess it would be a case of price vs. benefit. Would you be willing to pay $200 a vial of insulin for C-Peptide to be added to it? Yes, it may prevent complications but there's millions of diabetics out there that have no complications and have been on insulin. Then this would just add to the insurance problems and increase rates quite a bit.

[Funnygrl]

Originally Posted by xMenace

Even though there are claims that they would help us ward off complications.

YouTube - Love Diabetes: The blasphemy of C-peptide Removal

Honestly, watch enough of her stuff, and you get a pretty good feel for, oh, I dunno, you just get a good feel for her.

[lottadata]

This is a misunderstanding of the insulin production process. C-peptide is a by product of an intermediate step in the process by which your beta cell makes insulin.

But when they make insulin at a drug company, they have a little genetically modified bacteria make insulin molecules using the pattern inserted in the modified gene. No C-peptide is ever made.


But because C-peptide only is created when one of your own beta cells makes some insulin, testing it tells the doctor if you are still making insulin, whether or not you are injecting. It does NOT give a good idea of exactly how much you are capable of making, though. If you are injecting insulin you may be suppressing your own insulin production and hence your C-peptide might be lower than it otherwise would be. Doctors look at C-peptide mainly to see if you are a true Type 1 or not. True Type 1s have almost no C-peptide at all because their beta cells have been destroyed.

[owlyn]

Originally Posted by lottadata

True Type 1s have almost no C-peptide at all because their beta cells have been destroyed.

I am the truest type 1 there is. My c-peptide level was, "undetectable". Can't get much lower than that.

[parrotletzoo]

Originally Posted by Funnygrl

Honestly, watch enough of her stuff, and you get a pretty good feel for, oh, I dunno, you just get a good feel for her.

Yeah, exactly what funnygrl said there. Watch a few of her videos and you'll understand...